Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions

Transcriptional regulation is coupled with chromosomal positioning and chromatin architecture. Here the authors develop a transcriptional decomposition approach to separate expression associated with genome structure from independent effects not directly associated with genomic positioning.

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Auteurs principaux: Sarah Rennie, Maria Dalby, Lucas van Duin, Robin Andersson
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/8fba3c63d1ce45de95bd48d281f5b53b
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Résumé:Transcriptional regulation is coupled with chromosomal positioning and chromatin architecture. Here the authors develop a transcriptional decomposition approach to separate expression associated with genome structure from independent effects not directly associated with genomic positioning.