Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions
Transcriptional regulation is coupled with chromosomal positioning and chromatin architecture. Here the authors develop a transcriptional decomposition approach to separate expression associated with genome structure from independent effects not directly associated with genomic positioning.
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Nature Portfolio
2018
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oai:doaj.org-article:8fba3c63d1ce45de95bd48d281f5b53b2021-12-02T14:40:09ZTranscriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions10.1038/s41467-017-02798-12041-1723https://doaj.org/article/8fba3c63d1ce45de95bd48d281f5b53b2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02798-1https://doaj.org/toc/2041-1723Transcriptional regulation is coupled with chromosomal positioning and chromatin architecture. Here the authors develop a transcriptional decomposition approach to separate expression associated with genome structure from independent effects not directly associated with genomic positioning.Sarah RennieMaria DalbyLucas van DuinRobin AnderssonNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-16 (2018) |
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Science Q Sarah Rennie Maria Dalby Lucas van Duin Robin Andersson Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions |
description |
Transcriptional regulation is coupled with chromosomal positioning and chromatin architecture. Here the authors develop a transcriptional decomposition approach to separate expression associated with genome structure from independent effects not directly associated with genomic positioning. |
format |
article |
author |
Sarah Rennie Maria Dalby Lucas van Duin Robin Andersson |
author_facet |
Sarah Rennie Maria Dalby Lucas van Duin Robin Andersson |
author_sort |
Sarah Rennie |
title |
Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions |
title_short |
Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions |
title_full |
Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions |
title_fullStr |
Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions |
title_full_unstemmed |
Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions |
title_sort |
transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/8fba3c63d1ce45de95bd48d281f5b53b |
work_keys_str_mv |
AT sarahrennie transcriptionaldecompositionrevealsactivechromatinarchitecturesandcellspecificregulatoryinteractions AT mariadalby transcriptionaldecompositionrevealsactivechromatinarchitecturesandcellspecificregulatoryinteractions AT lucasvanduin transcriptionaldecompositionrevealsactivechromatinarchitecturesandcellspecificregulatoryinteractions AT robinandersson transcriptionaldecompositionrevealsactivechromatinarchitecturesandcellspecificregulatoryinteractions |
_version_ |
1718390429932584960 |