Transcriptional regulation is a major controller of cell cycle transition dynamics.

DNA replication, mitosis and mitotic exit are critical transitions of the cell cycle which normally occur only once per cycle. A universal control mechanism was proposed for the regulation of mitotic entry in which Cdk helps its own activation through two positive feedback loops. Recent discoveries...

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Bibliographic Details
Main Authors: Alessandro Romanel, Lars Juhl Jensen, Luca Cardelli, Attila Csikász-Nagy
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
R
Q
Online Access:https://doaj.org/article/8fbbe216d7a347c69b8832ad8c46fbb9
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