Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.)
Many of mimic analogues synthesized before depending on the change in the structure of aromatic rings. In this work, the carbonyl group in the structure of compounds 1-4 converted to thiocarbonyl group, and then studying the toxicological activity due to chemical change in the active center...
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Growing Science
2022
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oai:doaj.org-article:8fc09fe64bf04b2abb3e04e78d034e6b2021-11-12T12:52:42ZSynthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.)1927-72961927-730X10.5267/j.ccl.2021.9.005https://doaj.org/article/8fc09fe64bf04b2abb3e04e78d034e6b2022-01-01T00:00:00Zhttp://www.growingscience.com/ccl/Vol11/ccl_2021_36.pdfhttps://doaj.org/toc/1927-7296https://doaj.org/toc/1927-730X Many of mimic analogues synthesized before depending on the change in the structure of aromatic rings. In this work, the carbonyl group in the structure of compounds 1-4 converted to thiocarbonyl group, and then studying the toxicological activity due to chemical change in the active center of mimic analogues was performed for compounds N-tert-butyl-2,4-dichloro-N'-(2,4-dichlorobenzoyl)benzohydrazide (2) and N-tert-butyl-2,4-dichloro-N'-[(2,4-dichlorophenyl)carbonothioyl]benzenecarbothiohydrazide (6). The toxicological study was done by using 2nd and 4th instar larvae of the cotton leaf worm, Spodoptera littoralis (Boisd.). Five concentration levels (600, 300, 150, 75 and 37.5 ppm) of compounds (2) and (6) were applied on the fresh plant food to the newly grown (2nd and 4th) instar larvae.Omar M. ElhadyErian. S. MansourM. M. ElwassimySameh A. ZawamAli M. DrarGrowing SciencearticleChemistryQD1-999ENCurrent Chemistry Letters, Vol 11, Iss 1, Pp 63-68 (2022) |
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Chemistry QD1-999 Omar M. Elhady Erian. S. Mansour M. M. Elwassimy Sameh A. Zawam Ali M. Drar Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.) |
description |
Many of mimic analogues synthesized before depending on the change in the structure of aromatic rings. In this work, the carbonyl group in the structure of compounds 1-4 converted to thiocarbonyl group, and then studying the toxicological activity due to chemical change in the active center of mimic analogues was performed for compounds N-tert-butyl-2,4-dichloro-N'-(2,4-dichlorobenzoyl)benzohydrazide (2) and N-tert-butyl-2,4-dichloro-N'-[(2,4-dichlorophenyl)carbonothioyl]benzenecarbothiohydrazide (6). The toxicological study was done by using 2nd and 4th instar larvae of the cotton leaf worm, Spodoptera littoralis (Boisd.). Five concentration levels (600, 300, 150, 75 and 37.5 ppm) of compounds (2) and (6) were applied on the fresh plant food to the newly grown (2nd and 4th) instar larvae. |
format |
article |
author |
Omar M. Elhady Erian. S. Mansour M. M. Elwassimy Sameh A. Zawam Ali M. Drar |
author_facet |
Omar M. Elhady Erian. S. Mansour M. M. Elwassimy Sameh A. Zawam Ali M. Drar |
author_sort |
Omar M. Elhady |
title |
Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.) |
title_short |
Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.) |
title_full |
Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.) |
title_fullStr |
Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.) |
title_full_unstemmed |
Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.) |
title_sort |
synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against spodoptera littoralis (boisd.) |
publisher |
Growing Science |
publishDate |
2022 |
url |
https://doaj.org/article/8fc09fe64bf04b2abb3e04e78d034e6b |
work_keys_str_mv |
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