Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.)

Many of mimic analogues synthesized before depending on the change in the structure of aromatic rings. In this work, the carbonyl group in the structure of compounds 1-4 converted to thiocarbonyl group, and then studying the toxicological activity due to chemical change in the active center...

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Autores principales: Omar M. Elhady, Erian. S. Mansour, M. M. Elwassimy, Sameh A. Zawam, Ali M. Drar
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Publicado: Growing Science 2022
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spelling oai:doaj.org-article:8fc09fe64bf04b2abb3e04e78d034e6b2021-11-12T12:52:42ZSynthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.)1927-72961927-730X10.5267/j.ccl.2021.9.005https://doaj.org/article/8fc09fe64bf04b2abb3e04e78d034e6b2022-01-01T00:00:00Zhttp://www.growingscience.com/ccl/Vol11/ccl_2021_36.pdfhttps://doaj.org/toc/1927-7296https://doaj.org/toc/1927-730X Many of mimic analogues synthesized before depending on the change in the structure of aromatic rings. In this work, the carbonyl group in the structure of compounds 1-4 converted to thiocarbonyl group, and then studying the toxicological activity due to chemical change in the active center of mimic analogues was performed for compounds N-tert-butyl-2,4-dichloro-N'-(2,4-dichlorobenzoyl)benzohydrazide (2) and N-tert-butyl-2,4-dichloro-N'-[(2,4-dichlorophenyl)carbonothioyl]benzenecarbothiohydrazide (6). The toxicological study was done by using 2nd and 4th instar larvae of the cotton leaf worm, Spodoptera littoralis (Boisd.). Five concentration levels (600, 300, 150, 75 and 37.5 ppm) of compounds (2) and (6) were applied on the fresh plant food to the newly grown (2nd and 4th) instar larvae.Omar M. ElhadyErian. S. MansourM. M. ElwassimySameh A. ZawamAli M. DrarGrowing SciencearticleChemistryQD1-999ENCurrent Chemistry Letters, Vol 11, Iss 1, Pp 63-68 (2022)
institution DOAJ
collection DOAJ
language EN
topic Chemistry
QD1-999
spellingShingle Chemistry
QD1-999
Omar M. Elhady
Erian. S. Mansour
M. M. Elwassimy
Sameh A. Zawam
Ali M. Drar
Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.)
description Many of mimic analogues synthesized before depending on the change in the structure of aromatic rings. In this work, the carbonyl group in the structure of compounds 1-4 converted to thiocarbonyl group, and then studying the toxicological activity due to chemical change in the active center of mimic analogues was performed for compounds N-tert-butyl-2,4-dichloro-N'-(2,4-dichlorobenzoyl)benzohydrazide (2) and N-tert-butyl-2,4-dichloro-N'-[(2,4-dichlorophenyl)carbonothioyl]benzenecarbothiohydrazide (6). The toxicological study was done by using 2nd and 4th instar larvae of the cotton leaf worm, Spodoptera littoralis (Boisd.). Five concentration levels (600, 300, 150, 75 and 37.5 ppm) of compounds (2) and (6) were applied on the fresh plant food to the newly grown (2nd and 4th) instar larvae.
format article
author Omar M. Elhady
Erian. S. Mansour
M. M. Elwassimy
Sameh A. Zawam
Ali M. Drar
author_facet Omar M. Elhady
Erian. S. Mansour
M. M. Elwassimy
Sameh A. Zawam
Ali M. Drar
author_sort Omar M. Elhady
title Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.)
title_short Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.)
title_full Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.)
title_fullStr Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.)
title_full_unstemmed Synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against Spodoptera littoralis (Boisd.)
title_sort synthesis and characterization of some new tebufenozide analogues and study their toxicological effect against spodoptera littoralis (boisd.)
publisher Growing Science
publishDate 2022
url https://doaj.org/article/8fc09fe64bf04b2abb3e04e78d034e6b
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