Surfactant protein d deficiency in mice is associated with hyperphagia, altered fat deposition, insulin resistance, and increased basal endotoxemia.
Pulmonary surfactant protein D (SP-D) is a host defence lectin of the innate immune system that enhances clearance of pathogens and modulates inflammatory responses. Recently it has been found that systemic SP-D is associated with metabolic disturbances and that SP-D deficient mice are mildly obese....
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Autores principales: | Jacob V Stidsen, Reza Khorooshi, Martin K U Rahbek, Katrine L Kirketerp-Møller, Pernille B L Hansen, Peter Bie, Karin Kejling, Susanne Mandrup, Samuel Hawgood, Ole Nielsen, Claus H Nielsen, Trevor Owens, Uffe Holmskov, Grith L Sørensen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/8fc85292689b4985ab96e168c8f288eb |
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