THE EFFECT OF NIVOLUMAB IN PEDIATRIC MALIGNANT TUMORS: A SINGLE CENTER EXPERIENCE WITH EIGHT PATIENTS
Objective: The programmed cell death 1 (PD-1) receptor is an immune checkpoint receptor expressed by activated T cells. PD-1 inhibits the immune system by binding to its ligands expressed on tumor cells. Nivolumab and pembrolizumab are some of the monoclonal antibodies that inhibit the PD-1. We pres...
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Main Authors: | , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Elsevier
2021
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Subjects: | |
Online Access: | https://doaj.org/article/8fc9fac9b6054cc2b9b1c3e60f6e9bd4 |
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