Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure

Invariant natural killer T cells are known to be composed of a number of phenotypic and functionally distinct populations. Here the authors use transcriptomic and epigenomic analysis to further characterize the peripheral iNKT compartment before and after antigenic stimulation.

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Autores principales: Mallory Paynich Murray, Isaac Engel, Grégory Seumois, Sara Herrera-De la Mata, Sandy Lucette Rosales, Ashu Sethi, Ashmitaa Logandha Ramamoorthy Premlal, Goo-Young Seo, Jason Greenbaum, Pandurangan Vijayanand, James P. Scott-Browne, Mitchell Kronenberg
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8fd3eb5a36ea4cf5a286dfc60609479d
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spelling oai:doaj.org-article:8fd3eb5a36ea4cf5a286dfc60609479d2021-12-02T13:30:08ZTranscriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure10.1038/s41467-021-21574-w2041-1723https://doaj.org/article/8fd3eb5a36ea4cf5a286dfc60609479d2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21574-whttps://doaj.org/toc/2041-1723Invariant natural killer T cells are known to be composed of a number of phenotypic and functionally distinct populations. Here the authors use transcriptomic and epigenomic analysis to further characterize the peripheral iNKT compartment before and after antigenic stimulation.Mallory Paynich MurrayIsaac EngelGrégory SeumoisSara Herrera-De la MataSandy Lucette RosalesAshu SethiAshmitaa Logandha Ramamoorthy PremlalGoo-Young SeoJason GreenbaumPandurangan VijayanandJames P. Scott-BrowneMitchell KronenbergNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mallory Paynich Murray
Isaac Engel
Grégory Seumois
Sara Herrera-De la Mata
Sandy Lucette Rosales
Ashu Sethi
Ashmitaa Logandha Ramamoorthy Premlal
Goo-Young Seo
Jason Greenbaum
Pandurangan Vijayanand
James P. Scott-Browne
Mitchell Kronenberg
Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure
description Invariant natural killer T cells are known to be composed of a number of phenotypic and functionally distinct populations. Here the authors use transcriptomic and epigenomic analysis to further characterize the peripheral iNKT compartment before and after antigenic stimulation.
format article
author Mallory Paynich Murray
Isaac Engel
Grégory Seumois
Sara Herrera-De la Mata
Sandy Lucette Rosales
Ashu Sethi
Ashmitaa Logandha Ramamoorthy Premlal
Goo-Young Seo
Jason Greenbaum
Pandurangan Vijayanand
James P. Scott-Browne
Mitchell Kronenberg
author_facet Mallory Paynich Murray
Isaac Engel
Grégory Seumois
Sara Herrera-De la Mata
Sandy Lucette Rosales
Ashu Sethi
Ashmitaa Logandha Ramamoorthy Premlal
Goo-Young Seo
Jason Greenbaum
Pandurangan Vijayanand
James P. Scott-Browne
Mitchell Kronenberg
author_sort Mallory Paynich Murray
title Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure
title_short Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure
title_full Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure
title_fullStr Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure
title_full_unstemmed Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure
title_sort transcriptome and chromatin landscape of inkt cells are shaped by subset differentiation and antigen exposure
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8fd3eb5a36ea4cf5a286dfc60609479d
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