Glycan-dependent cell adhesion mechanism of Tc toxins
Although Tc toxins are a major class of bacterial toxin translocation systems, little is known about their receptor binding. Here, the authors identify heparins/heparan sulfates and Lewis antigens as receptors for different Tc toxins, determine cryo-EM structures of three toxin-glycan complexes and...
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Main Authors: | Daniel Roderer, Felix Bröcker, Oleg Sitsel, Paulina Kaplonek, Franziska Leidreiter, Peter H. Seeberger, Stefan Raunser |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Online Access: | https://doaj.org/article/8fd46558833e4d1b98f8b3ad1804b7b8 |
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