Intranasal immunization with inactivated chlamydial elementary bodies formulated in VCG-chitosan nanoparticles induces robust immunity against intranasal Chlamydia psittaci challenge

Abstract Vaccines based on live attenuated Chlamydia elementary bodies (EBs) can cause disease in vaccinated animals and the comparably safer inactivated whole EBs are only marginally protective. Recent studies show that a vaccine formulation comprising UV-inactivated EBs (EB) and appropriate mucosa...

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Autores principales: Zonghui Zuo, Yongjuan Zou, Qiang Li, Yongxia Guo, Tianyuan Zhang, Jie Wu, Cheng He, Francis O. Eko
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8fd97ec6e19a4235a29c2fa8339311db
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