The role of hypoxia-inducible factor 1α in determining the properties of castrate-resistant prostate cancers.

The role of hypoxia-inducible factor 1α in determining the properties of castrate-resistant prostate cancers.

<h4>Background</h4>Castrate-resistant prostate cancer (CRPC) is a lethal condition in patients receiving androgen deprivation therapy for prostate cancer (PC). Despite numerous studies showing the expression of HIF1α protein under normoxia in PC cell lines, the role of this normoxic HIF1...

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Autores principales: Weranja K B Ranasinghe, Lin Xiao, Suzana Kovac, Mike Chang, Carine Michiels, Damien Bolton, Arthur Shulkes, Graham S Baldwin, Oneel Patel
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/8fdcdc1151e14acaa32d31f37447b1a2
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