Cell Dispersal Influences Tumor Heterogeneity and Introduces a Bias in NGS Data Interpretation

Abstract Short and long distance cell dispersal can have a marked effect on tumor structure, high cellular motility could lead to faster cell mixing and lower observable intratumor heterogeneity. Here we evaluated a model for cell mixing that investigates how short-range dispersal and cell turnover...

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Autores principales: Lőrinc Pongor, Hajnalka Harami-Papp, Előd Méhes, András Czirók, Balázs Győrffy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8fe08173e9b344939e6095849762a2a4
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