Cell Dispersal Influences Tumor Heterogeneity and Introduces a Bias in NGS Data Interpretation
Abstract Short and long distance cell dispersal can have a marked effect on tumor structure, high cellular motility could lead to faster cell mixing and lower observable intratumor heterogeneity. Here we evaluated a model for cell mixing that investigates how short-range dispersal and cell turnover...
Guardado en:
Autores principales: | Lőrinc Pongor, Hajnalka Harami-Papp, Előd Méhes, András Czirók, Balázs Győrffy |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/8fe08173e9b344939e6095849762a2a4 |
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