Evolving application of biomimetic nanostructured hydroxyapatite

Norberto Roveri, Michele IafiscoLaboratory of Environmental and Biological Structural Chemistry (LEBSC), Dipartimento di Chimica &lsquo;G. Ciamician&rsquo;, Alma Mater Studiorum, Universit&agrave; di Bologna, Bologna, ItalyAbstract: By mimicking Nature, we can design and synt...

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Autores principales:	Norberto Roveri, Michele Iafisco
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Medical technology R855-855.5 Chemical technology TP1-1185
Acceso en línea:	https://doaj.org/article/8fe31ef0e8934253852006a104bca966
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spelling	oai:doaj.org-article:8fe31ef0e8934253852006a104bca9662021-12-02T05:25:50ZEvolving application of biomimetic nanostructured hydroxyapatite1177-8903https://doaj.org/article/8fe31ef0e8934253852006a104bca9662010-11-01T00:00:00Zhttp://www.dovepress.com/evolving-application-of-biomimetic-nanostructured-hydroxyapatite-a5618https://doaj.org/toc/1177-8903Norberto Roveri, Michele IafiscoLaboratory of Environmental and Biological Structural Chemistry (LEBSC), Dipartimento di Chimica &lsquo;G. Ciamician&rsquo;, Alma Mater Studiorum, Universit&agrave; di Bologna, Bologna, ItalyAbstract: By mimicking Nature, we can design and synthesize inorganic smart materials that are reactive to biological tissues. These smart materials can be utilized to design innovative third-generation biomaterials, which are able to not only optimize their interaction with biological tissues and environment, but also mimic biogenic materials in their functionalities. The biomedical applications involve increasing the biomimetic levels from chemical composition, structural organization, morphology, mechanical behavior, nanostructure, and bulk and surface chemical&ndash;physical properties until the surface becomes bioreactive and stimulates cellular materials. The chemical&ndash;physical characteristics of biogenic hydroxyapatites from bone and tooth have been described, in order to point out the elective sides, which are important to reproduce the design of a new biomimetic synthetic hydroxyapatite. This review outlines the evolving applications of biomimetic synthetic calcium phosphates, details the main characteristics of bone and tooth, where the calcium phosphates are present, and discusses the chemical&ndash;physical characteristics of biomimetic calcium phosphates, methods of synthesizing them, and some of their biomedical applications.Keywords: hydroxyapatite, nanocrystals, biomimetism, biomaterials, drug delivery, remineralization Norberto RoveriMichele IafiscoDove Medical PressarticleMedical technologyR855-855.5Chemical technologyTP1-1185ENNanotechnology, Science and Applications, Vol 2010, Iss default, Pp 107-125 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medical technology R855-855.5 Chemical technology TP1-1185
spellingShingle	Medical technology R855-855.5 Chemical technology TP1-1185 Norberto Roveri Michele Iafisco Evolving application of biomimetic nanostructured hydroxyapatite
description	Norberto Roveri, Michele IafiscoLaboratory of Environmental and Biological Structural Chemistry (LEBSC), Dipartimento di Chimica &lsquo;G. Ciamician&rsquo;, Alma Mater Studiorum, Universit&agrave; di Bologna, Bologna, ItalyAbstract: By mimicking Nature, we can design and synthesize inorganic smart materials that are reactive to biological tissues. These smart materials can be utilized to design innovative third-generation biomaterials, which are able to not only optimize their interaction with biological tissues and environment, but also mimic biogenic materials in their functionalities. The biomedical applications involve increasing the biomimetic levels from chemical composition, structural organization, morphology, mechanical behavior, nanostructure, and bulk and surface chemical&ndash;physical properties until the surface becomes bioreactive and stimulates cellular materials. The chemical&ndash;physical characteristics of biogenic hydroxyapatites from bone and tooth have been described, in order to point out the elective sides, which are important to reproduce the design of a new biomimetic synthetic hydroxyapatite. This review outlines the evolving applications of biomimetic synthetic calcium phosphates, details the main characteristics of bone and tooth, where the calcium phosphates are present, and discusses the chemical&ndash;physical characteristics of biomimetic calcium phosphates, methods of synthesizing them, and some of their biomedical applications.Keywords: hydroxyapatite, nanocrystals, biomimetism, biomaterials, drug delivery, remineralization
format	article
author	Norberto Roveri Michele Iafisco
author_facet	Norberto Roveri Michele Iafisco
author_sort	Norberto Roveri
title	Evolving application of biomimetic nanostructured hydroxyapatite
title_short	Evolving application of biomimetic nanostructured hydroxyapatite
title_full	Evolving application of biomimetic nanostructured hydroxyapatite
title_fullStr	Evolving application of biomimetic nanostructured hydroxyapatite
title_full_unstemmed	Evolving application of biomimetic nanostructured hydroxyapatite
title_sort	evolving application of biomimetic nanostructured hydroxyapatite
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/8fe31ef0e8934253852006a104bca966
work_keys_str_mv	AT norbertoroveri evolvingapplicationofbiomimeticnanostructuredhydroxyapatite AT micheleiafisco evolvingapplicationofbiomimeticnanostructuredhydroxyapatite
_version_	1718400428524175360

Evolving application of biomimetic nanostructured hydroxyapatite

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