Functional characterization of TLR4 +3725 G/C polymorphism and association with protection against overweight.

Functional characterization of TLR4 +3725 G/C polymorphism and association with protection against overweight.

Subclinical low-grade systemic inflammation has been associated with obesity, insulin resistance and metabolic syndrome (MS). Recent studies have highlighted the role of gut microbiota in these disorders. The toll-like receptor 4 (TLR4) plays a key role in the innate immune response activation. We s...

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Main Authors: Alberto Penas-Steinhardt, Lucía Soledad Barcos, Fiorella Sabrina Belforte, Martha de Sereday, Jorge Vilariño, Claudio Daniel Gonzalez, María Teresa Martínez-Larrad, Mariana Lorena Tellechea, Manuel Serrano-Ríos, Edgardo Poskus, Gustavo Daniel Frechtel, Federico Coluccio Leskow
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/8fe5115bd0284c0fa5572413abc0ba0e
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https://doaj.org/article/8fe5115bd0284c0fa5572413abc0ba0e

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