Observation of posterior corneal vesicles with in vivo confocal microscopy and anterior segment OCT
Ryou Watanabe, Toru Nakazawa, Nobuo FuseDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, JapanAbstract: The histopathology of posterior corneal vesicles (PCV) has not yet been revealed. A 15-year-old girl, who was diagnosed by slit-lamp microscopy as PCV, was exami...
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Dove Medical Press
2010
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oai:doaj.org-article:8fe55e5399ec4e67b8c9eac604d785602021-12-02T00:49:22ZObservation of posterior corneal vesicles with in vivo confocal microscopy and anterior segment OCT1177-54671177-5483https://doaj.org/article/8fe55e5399ec4e67b8c9eac604d785602010-10-01T00:00:00Zhttp://www.dovepress.com/observation-of-posterior-corneal-vesicles-with-in-vivo-confocal-micros-a5550https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Ryou Watanabe, Toru Nakazawa, Nobuo FuseDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, JapanAbstract: The histopathology of posterior corneal vesicles (PCV) has not yet been revealed. A 15-year-old girl, who was diagnosed by slit-lamp microscopy as PCV, was examined using specular microscopy, in vivo confocal microscopy, and anterior segment OCT (optical coherence tomography). Anterior segment OCT showed that the thickness of both corneas was within normal limits. At the same time, in vivo confocal microscopy revealed endothelial cells in the rounded dark areas, acellular hyporeflective layers on the Descemet’s membrane, and hyperreflective linear lesions. These findings were not reported previously by slit-lamp and specular microscopy. The abnormal findings only existed at the Descemet’s membrane and corneal endothelial layer. Previous reports dealing with posterior polymorphous dystrophy (PPMD) examined using in vivo confocal microscopy reported almost the same findings, suggesting that PCV and PPMD may be the same at the microstructural level.Keywords: cornea, Descemet’s membrane, imaging Ryou WatanabeToru NakazawaNobuo FuseDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 1243-1247 (2010) |
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Ophthalmology RE1-994 |
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Ophthalmology RE1-994 Ryou Watanabe Toru Nakazawa Nobuo Fuse Observation of posterior corneal vesicles with in vivo confocal microscopy and anterior segment OCT |
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Ryou Watanabe, Toru Nakazawa, Nobuo FuseDepartment of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, JapanAbstract: The histopathology of posterior corneal vesicles (PCV) has not yet been revealed. A 15-year-old girl, who was diagnosed by slit-lamp microscopy as PCV, was examined using specular microscopy, in vivo confocal microscopy, and anterior segment OCT (optical coherence tomography). Anterior segment OCT showed that the thickness of both corneas was within normal limits. At the same time, in vivo confocal microscopy revealed endothelial cells in the rounded dark areas, acellular hyporeflective layers on the Descemet’s membrane, and hyperreflective linear lesions. These findings were not reported previously by slit-lamp and specular microscopy. The abnormal findings only existed at the Descemet’s membrane and corneal endothelial layer. Previous reports dealing with posterior polymorphous dystrophy (PPMD) examined using in vivo confocal microscopy reported almost the same findings, suggesting that PCV and PPMD may be the same at the microstructural level.Keywords: cornea, Descemet’s membrane, imaging |
format |
article |
author |
Ryou Watanabe Toru Nakazawa Nobuo Fuse |
author_facet |
Ryou Watanabe Toru Nakazawa Nobuo Fuse |
author_sort |
Ryou Watanabe |
title |
Observation of posterior corneal vesicles with in vivo confocal microscopy and anterior segment OCT |
title_short |
Observation of posterior corneal vesicles with in vivo confocal microscopy and anterior segment OCT |
title_full |
Observation of posterior corneal vesicles with in vivo confocal microscopy and anterior segment OCT |
title_fullStr |
Observation of posterior corneal vesicles with in vivo confocal microscopy and anterior segment OCT |
title_full_unstemmed |
Observation of posterior corneal vesicles with in vivo confocal microscopy and anterior segment OCT |
title_sort |
observation of posterior corneal vesicles with in vivo confocal microscopy and anterior segment oct |
publisher |
Dove Medical Press |
publishDate |
2010 |
url |
https://doaj.org/article/8fe55e5399ec4e67b8c9eac604d78560 |
work_keys_str_mv |
AT ryouwatanabe observationofposteriorcornealvesicleswithinvivoconfocalmicroscopyandanteriorsegmentoct AT torunakazawa observationofposteriorcornealvesicleswithinvivoconfocalmicroscopyandanteriorsegmentoct AT nobuofuse observationofposteriorcornealvesicleswithinvivoconfocalmicroscopyandanteriorsegmentoct |
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