Impact of exercise capacity on the long-term incidence of atrial arrhythmias in heart failure

Abstract We sought to demonstrate the impact of improved peak exercise oxygen consumption (V̇O2) during maximal exercise testing after cardiac rehabilitation (CR) on the incidence of arrhythmias in patients with heart failure (HF). The present study comprised of 220 patients with HF, and peak V̇O2 w...

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Autores principales:	Tetsuri Sakai, Atsuhiko Yagishita, Masahiro Morise, Susumu Sakama, Takeshi Ijichi, Kengo Ayabe, Mari Amino, Yuji Ikari, Koichiro Yoshioka
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8feca7905147473db80536db082be938
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spelling	oai:doaj.org-article:8feca7905147473db80536db082be9382021-12-02T15:14:48ZImpact of exercise capacity on the long-term incidence of atrial arrhythmias in heart failure10.1038/s41598-021-98172-92045-2322https://doaj.org/article/8feca7905147473db80536db082be9382021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-98172-9https://doaj.org/toc/2045-2322Abstract We sought to demonstrate the impact of improved peak exercise oxygen consumption (V̇O2) during maximal exercise testing after cardiac rehabilitation (CR) on the incidence of arrhythmias in patients with heart failure (HF). The present study comprised of 220 patients with HF, and peak V̇O2 was examined at 2 and 5 months after CR. Of the 220 patients, 110 (50%) had a low peak V̇O2 of < 14 mL/min/kg at 2 months. The peak V̇O2 improved in 86 of these 110 (78%) patients at 5 months after CR. During a median follow-up of 6 years, the patients with improvement in peak V̇O2, compared to those without peak V̇O2 improvement, had a lower rate of mortality (4% vs. 29%, log-rank, P < 0.001) and HF hospitalization (6 vs. 17%, log-rank, P = 0.044) and a lower incidence of new-onset atrial arrhythmias (9 vs. 27%, log-rank, P = 0.013), with no difference in the incidence of ventricular arrhythmias between groups (1 vs. 4%, log-rank, P = 0.309). The majority of deaths in the patients without an improved peak V̇O2 were because of cardiovascular events (73%), particularly progressive HF (55%). Early detection and management of atrial arrhythmias may improve outcomes in patients without peak V̇O2 improvement after CR.Tetsuri SakaiAtsuhiko YagishitaMasahiro MoriseSusumu SakamaTakeshi IjichiKengo AyabeMari AminoYuji IkariKoichiro YoshiokaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Tetsuri Sakai Atsuhiko Yagishita Masahiro Morise Susumu Sakama Takeshi Ijichi Kengo Ayabe Mari Amino Yuji Ikari Koichiro Yoshioka Impact of exercise capacity on the long-term incidence of atrial arrhythmias in heart failure
description	Abstract We sought to demonstrate the impact of improved peak exercise oxygen consumption (V̇O2) during maximal exercise testing after cardiac rehabilitation (CR) on the incidence of arrhythmias in patients with heart failure (HF). The present study comprised of 220 patients with HF, and peak V̇O2 was examined at 2 and 5 months after CR. Of the 220 patients, 110 (50%) had a low peak V̇O2 of < 14 mL/min/kg at 2 months. The peak V̇O2 improved in 86 of these 110 (78%) patients at 5 months after CR. During a median follow-up of 6 years, the patients with improvement in peak V̇O2, compared to those without peak V̇O2 improvement, had a lower rate of mortality (4% vs. 29%, log-rank, P < 0.001) and HF hospitalization (6 vs. 17%, log-rank, P = 0.044) and a lower incidence of new-onset atrial arrhythmias (9 vs. 27%, log-rank, P = 0.013), with no difference in the incidence of ventricular arrhythmias between groups (1 vs. 4%, log-rank, P = 0.309). The majority of deaths in the patients without an improved peak V̇O2 were because of cardiovascular events (73%), particularly progressive HF (55%). Early detection and management of atrial arrhythmias may improve outcomes in patients without peak V̇O2 improvement after CR.
format	article
author	Tetsuri Sakai Atsuhiko Yagishita Masahiro Morise Susumu Sakama Takeshi Ijichi Kengo Ayabe Mari Amino Yuji Ikari Koichiro Yoshioka
author_facet	Tetsuri Sakai Atsuhiko Yagishita Masahiro Morise Susumu Sakama Takeshi Ijichi Kengo Ayabe Mari Amino Yuji Ikari Koichiro Yoshioka
author_sort	Tetsuri Sakai
title	Impact of exercise capacity on the long-term incidence of atrial arrhythmias in heart failure
title_short	Impact of exercise capacity on the long-term incidence of atrial arrhythmias in heart failure
title_full	Impact of exercise capacity on the long-term incidence of atrial arrhythmias in heart failure
title_fullStr	Impact of exercise capacity on the long-term incidence of atrial arrhythmias in heart failure
title_full_unstemmed	Impact of exercise capacity on the long-term incidence of atrial arrhythmias in heart failure
title_sort	impact of exercise capacity on the long-term incidence of atrial arrhythmias in heart failure
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8feca7905147473db80536db082be938
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Impact of exercise capacity on the long-term incidence of atrial arrhythmias in heart failure

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