Genetically engineered frameshifted YopN-TyeA chimeras influence type III secretion system function in Yersinia pseudotuberculosis.

Genetically engineered frameshifted YopN-TyeA chimeras influence type III secretion system function in Yersinia pseudotuberculosis.

Type III secretion is a tightly controlled virulence mechanism utilized by many gram negative bacteria to colonize their eukaryotic hosts. To infect their host, human pathogenic Yersinia spp. translocate protein toxins into the host cell cytosol through a preassembled Ysc-Yop type III secretion devi...

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Autores principales: Ayad A A Amer, Tiago R D Costa, Salah I Farag, Ummehan Avican, Åke Forsberg, Matthew S Francis
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/8fee714e10cf451e90aec141e7a4b8c8
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