$Corneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery$
Código QR

Corneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery

Hon Shing Ong,1–3 Mohamed Farook,1 Benjamin Boon Chuan Tan,1 Geraint P Williams,1,2 Marcony R Santhiago,4,5 Jodhbir S Mehta1–3,6 1Department of Corneal and External Diseases, Singapore National Eye Centre, Singapore, Singapore; 2Tissue Engineering and Stem Cell Group, Si...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ong HS, Farook M, Tan BBC, Williams GP, Santhiago MR, Mehta JS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Percentage tissue altered ectasia refractive surgery laser in-situ keratomileusis laser-in-situ epithelial keratomileusis small incision lenticule extraction Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/8ff3d53c21084959a05f03816a9a6f2c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:8ff3d53c21084959a05f03816a9a6f2c
record_format	dspace
spelling	oai:doaj.org-article:8ff3d53c21084959a05f03816a9a6f2c2021-12-02T08:11:50ZCorneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery1177-5483https://doaj.org/article/8ff3d53c21084959a05f03816a9a6f2c2019-10-01T00:00:00Zhttps://www.dovepress.com/corneal-ectasia-risk-and-percentage-tissue-altered-in-myopic-patients--peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Hon Shing Ong,1–3 Mohamed Farook,1 Benjamin Boon Chuan Tan,1 Geraint P Williams,1,2 Marcony R Santhiago,4,5 Jodhbir S Mehta1–3,6 1Department of Corneal and External Diseases, Singapore National Eye Centre, Singapore, Singapore; 2Tissue Engineering and Stem Cell Group, Singapore Eye Research Institute, Singapore, Singapore; 3SingHealth Duke-NUS Ophthalmology and Visual Sciences Academic Clinical Programme, Duke-NUS Graduate Medical School, Singapore, Singapore; 4Department of Ophthalmology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; 5Department of Ophthalmology, University of Sao Paulo, Sao Paulo, Brazil; 6School of Material Science and Engineering, Nanyang Technological University, Singapore, SingaporeCorrespondence: Hon Shing Ong; Jodhbir S MehtaDepartment of Corneal and External Diseases, Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore168751, SingaporeTel +65 6227 7255Email honshing@gmail.com; jodmehta@gmail.comPurpose: A percentage tissue altered (PTA) score of ≥40% has been advocated as an independent indicator of post-operative ectasia risk following laser in-situ keratomileusis (LASIK). This study was performed to test the hypothesis that refractive procedures, such as laser-assisted sub-epithelial keratectomy (LASEK) or small incision lenticule extraction (SMILE), may alter the range of PTA, within which refractive corneal surgery can be safely performed.Setting: Refractive department, tertiary ophthalmic hospital.Design: Retrospective observational study.Methods: Review of case notes was performed for patients who presented for refractive surgeries, other than LASIK. To determine the risk of corneal ectasia for each patient prior to refractive surgery, we estimated what each patient’s PTA would have been if they had undergone LASIK. The Randleman Ectasia Risk Score System (ERSS) was also calculated.Results: 114 eyes (66 patients) were included. 94 eyes underwent SMILE. 20 eyes underwent LASEK. A significant proportion of eyes had PTA ≥40% – SMILE eyes: up to 31.9%, LASEK eyes: up to 60.0% (at presumed LASIK flap of 120 μm). The maximum calculated PTA was up to 47.9% in the SMILE group and up to 51.5% in the LASEK group. Using ERSS, 12.8–16% of SMILE eyes and 15.0–80.0% of LASEK eyes would have been considered to have moderate-to-high ectasia risk. No post-surgical ectasia was observed at 3 years.Conclusion: SMILE and LASEK alter the range of PTA, within which corneal refractive surgery may be performed with a lower risk of developing post-operative corneal ectasia; a safe PTA threshold needs to be determined for these procedures before recommendations for clinical practice can be made.Keywords: percentage tissue altered, ectasia, refractive surgery, laser in situ keratomileusis, laser-assisted sub-epithelial keratectomy, small incision lenticule extractionOng HSFarook MTan BBCWilliams GPSanthiago MRMehta JSDove Medical PressarticlePercentage tissue alteredectasiarefractive surgerylaser in-situ keratomileusislaser-in-situ epithelial keratomileusissmall incision lenticule extractionOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 13, Pp 2003-2015 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Percentage tissue altered ectasia refractive surgery laser in-situ keratomileusis laser-in-situ epithelial keratomileusis small incision lenticule extraction Ophthalmology RE1-994
spellingShingle	Percentage tissue altered ectasia refractive surgery laser in-situ keratomileusis laser-in-situ epithelial keratomileusis small incision lenticule extraction Ophthalmology RE1-994 Ong HS Farook M Tan BBC Williams GP Santhiago MR Mehta JS Corneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery
description	Hon Shing Ong,1–3 Mohamed Farook,1 Benjamin Boon Chuan Tan,1 Geraint P Williams,1,2 Marcony R Santhiago,4,5 Jodhbir S Mehta1–3,6 1Department of Corneal and External Diseases, Singapore National Eye Centre, Singapore, Singapore; 2Tissue Engineering and Stem Cell Group, Singapore Eye Research Institute, Singapore, Singapore; 3SingHealth Duke-NUS Ophthalmology and Visual Sciences Academic Clinical Programme, Duke-NUS Graduate Medical School, Singapore, Singapore; 4Department of Ophthalmology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; 5Department of Ophthalmology, University of Sao Paulo, Sao Paulo, Brazil; 6School of Material Science and Engineering, Nanyang Technological University, Singapore, SingaporeCorrespondence: Hon Shing Ong; Jodhbir S MehtaDepartment of Corneal and External Diseases, Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore168751, SingaporeTel +65 6227 7255Email honshing@gmail.com; jodmehta@gmail.comPurpose: A percentage tissue altered (PTA) score of ≥40% has been advocated as an independent indicator of post-operative ectasia risk following laser in-situ keratomileusis (LASIK). This study was performed to test the hypothesis that refractive procedures, such as laser-assisted sub-epithelial keratectomy (LASEK) or small incision lenticule extraction (SMILE), may alter the range of PTA, within which refractive corneal surgery can be safely performed.Setting: Refractive department, tertiary ophthalmic hospital.Design: Retrospective observational study.Methods: Review of case notes was performed for patients who presented for refractive surgeries, other than LASIK. To determine the risk of corneal ectasia for each patient prior to refractive surgery, we estimated what each patient’s PTA would have been if they had undergone LASIK. The Randleman Ectasia Risk Score System (ERSS) was also calculated.Results: 114 eyes (66 patients) were included. 94 eyes underwent SMILE. 20 eyes underwent LASEK. A significant proportion of eyes had PTA ≥40% – SMILE eyes: up to 31.9%, LASEK eyes: up to 60.0% (at presumed LASIK flap of 120 μm). The maximum calculated PTA was up to 47.9% in the SMILE group and up to 51.5% in the LASEK group. Using ERSS, 12.8–16% of SMILE eyes and 15.0–80.0% of LASEK eyes would have been considered to have moderate-to-high ectasia risk. No post-surgical ectasia was observed at 3 years.Conclusion: SMILE and LASEK alter the range of PTA, within which corneal refractive surgery may be performed with a lower risk of developing post-operative corneal ectasia; a safe PTA threshold needs to be determined for these procedures before recommendations for clinical practice can be made.Keywords: percentage tissue altered, ectasia, refractive surgery, laser in situ keratomileusis, laser-assisted sub-epithelial keratectomy, small incision lenticule extraction
format	article
author	Ong HS Farook M Tan BBC Williams GP Santhiago MR Mehta JS
author_facet	Ong HS Farook M Tan BBC Williams GP Santhiago MR Mehta JS
author_sort	Ong HS
title	Corneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery
title_short	Corneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery
title_full	Corneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery
title_fullStr	Corneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery
title_full_unstemmed	Corneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery
title_sort	corneal ectasia risk and percentage tissue altered in myopic patients presenting for refractive surgery
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/8ff3d53c21084959a05f03816a9a6f2c
work_keys_str_mv	AT onghs cornealectasiariskandpercentagetissuealteredinmyopicpatientspresentingforrefractivesurgery AT farookm cornealectasiariskandpercentagetissuealteredinmyopicpatientspresentingforrefractivesurgery AT tanbbc cornealectasiariskandpercentagetissuealteredinmyopicpatientspresentingforrefractivesurgery AT williamsgp cornealectasiariskandpercentagetissuealteredinmyopicpatientspresentingforrefractivesurgery AT santhiagomr cornealectasiariskandpercentagetissuealteredinmyopicpatientspresentingforrefractivesurgery AT mehtajs cornealectasiariskandpercentagetissuealteredinmyopicpatientspresentingforrefractivesurgery
_version_	1718398613619474432

Corneal Ectasia Risk And Percentage Tissue Altered In Myopic Patients Presenting For Refractive Surgery

Ejemplares similares