Real-Life Outcomes of Coronary Bifurcation Stenting in Acute Myocardial Infarction (Zabrze–Opole Registry)

Percutaneous coronary intervention (PCI) of bifurcation lesions is a technical challenge associated with high risk of adverse events, especially in primary PCI. The aim of the study is to analyze long-term outcomes after PCI for coronary bifurcation in acute myocardial infarction (AMI). The outcome...

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Autores principales:	Wojciech Milejski, Jerzy Sacha, Piotr Feusette, Marek Cisowski, Piotr Muzyk, Andrzej Tomasik, Marek Gierlotka, Beata Morawiec, Damian Kawecki
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	acute myocardial infarction coronary bifurcation percutaneous coronary intervention target lesion failure Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/8ff5eb6f914b4279b458373009d99b58
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spelling	oai:doaj.org-article:8ff5eb6f914b4279b458373009d99b582021-11-25T18:00:25ZReal-Life Outcomes of Coronary Bifurcation Stenting in Acute Myocardial Infarction (Zabrze–Opole Registry)10.3390/jcdd81101552308-3425https://doaj.org/article/8ff5eb6f914b4279b458373009d99b582021-11-01T00:00:00Zhttps://www.mdpi.com/2308-3425/8/11/155https://doaj.org/toc/2308-3425Percutaneous coronary intervention (PCI) of bifurcation lesions is a technical challenge associated with high risk of adverse events, especially in primary PCI. The aim of the study is to analyze long-term outcomes after PCI for coronary bifurcation in acute myocardial infarction (AMI). The outcome was defined as the rate of major adverse cardiac event related to target lesion failure (MACE-TLF) (death-TLF, nonfatal myocardial infarction-TLF and target lesion revascularization (TLR)) and the rate of stent thrombosis (ST). From 306 patients enrolled to the registry, 113 were diagnosed with AMI. In the long term, AMI was not a risk factor for MACE-TLF. The risk of MACE-TLF was dependent on the culprit lesion, especially in the right coronary artery (RCA) and side branch (SB) with a diameter >3 mm. When PCI was performed in the SB, the inflation pressure in SB remained the single risk factor of poor prognosis. The rate of cumulative ST driven by late ST in AMI was dependent on the inflation pressure in the main branch (MB). In conclusion, PCI of bifurcation culprit lesions should be performed carefully in case of RCA and large SB diameter and attention should be paid to high inflation pressure in the SB. On the contrary, the lower the inflation pressure in the MB, the higher the risk of ST.Wojciech MilejskiJerzy SachaPiotr FeusetteMarek CisowskiPiotr MuzykAndrzej TomasikMarek GierlotkaBeata MorawiecDamian KaweckiMDPI AGarticleacute myocardial infarctioncoronary bifurcationpercutaneous coronary interventiontarget lesion failureDiseases of the circulatory (Cardiovascular) systemRC666-701ENJournal of Cardiovascular Development and Disease, Vol 8, Iss 155, p 155 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	acute myocardial infarction coronary bifurcation percutaneous coronary intervention target lesion failure Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	acute myocardial infarction coronary bifurcation percutaneous coronary intervention target lesion failure Diseases of the circulatory (Cardiovascular) system RC666-701 Wojciech Milejski Jerzy Sacha Piotr Feusette Marek Cisowski Piotr Muzyk Andrzej Tomasik Marek Gierlotka Beata Morawiec Damian Kawecki Real-Life Outcomes of Coronary Bifurcation Stenting in Acute Myocardial Infarction (Zabrze–Opole Registry)
description	Percutaneous coronary intervention (PCI) of bifurcation lesions is a technical challenge associated with high risk of adverse events, especially in primary PCI. The aim of the study is to analyze long-term outcomes after PCI for coronary bifurcation in acute myocardial infarction (AMI). The outcome was defined as the rate of major adverse cardiac event related to target lesion failure (MACE-TLF) (death-TLF, nonfatal myocardial infarction-TLF and target lesion revascularization (TLR)) and the rate of stent thrombosis (ST). From 306 patients enrolled to the registry, 113 were diagnosed with AMI. In the long term, AMI was not a risk factor for MACE-TLF. The risk of MACE-TLF was dependent on the culprit lesion, especially in the right coronary artery (RCA) and side branch (SB) with a diameter >3 mm. When PCI was performed in the SB, the inflation pressure in SB remained the single risk factor of poor prognosis. The rate of cumulative ST driven by late ST in AMI was dependent on the inflation pressure in the main branch (MB). In conclusion, PCI of bifurcation culprit lesions should be performed carefully in case of RCA and large SB diameter and attention should be paid to high inflation pressure in the SB. On the contrary, the lower the inflation pressure in the MB, the higher the risk of ST.
format	article
author	Wojciech Milejski Jerzy Sacha Piotr Feusette Marek Cisowski Piotr Muzyk Andrzej Tomasik Marek Gierlotka Beata Morawiec Damian Kawecki
author_facet	Wojciech Milejski Jerzy Sacha Piotr Feusette Marek Cisowski Piotr Muzyk Andrzej Tomasik Marek Gierlotka Beata Morawiec Damian Kawecki
author_sort	Wojciech Milejski
title	Real-Life Outcomes of Coronary Bifurcation Stenting in Acute Myocardial Infarction (Zabrze–Opole Registry)
title_short	Real-Life Outcomes of Coronary Bifurcation Stenting in Acute Myocardial Infarction (Zabrze–Opole Registry)
title_full	Real-Life Outcomes of Coronary Bifurcation Stenting in Acute Myocardial Infarction (Zabrze–Opole Registry)
title_fullStr	Real-Life Outcomes of Coronary Bifurcation Stenting in Acute Myocardial Infarction (Zabrze–Opole Registry)
title_full_unstemmed	Real-Life Outcomes of Coronary Bifurcation Stenting in Acute Myocardial Infarction (Zabrze–Opole Registry)
title_sort	real-life outcomes of coronary bifurcation stenting in acute myocardial infarction (zabrze–opole registry)
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/8ff5eb6f914b4279b458373009d99b58
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Real-Life Outcomes of Coronary Bifurcation Stenting in Acute Myocardial Infarction (Zabrze–Opole Registry)

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