Influence of initial treatment modality on long-term control of chronic idiopathic urticaria.

<h4>Background</h4>Chronic idiopathic urticaria (CIU) is a common cutaneous disorder but the influence of initial treatment modality on long-term control is not known. The aim of this study was to evaluate clinical features, and the influence of initial treatment modality on long-term co...

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Autores principales:	Sujeong Kim, Seunghee Baek, Bomi Shin, Sun-young Yoon, So Young Park, Taehoon Lee, Yoon Su Lee, Yun-Jeong Bae, Hyouk Soo Kwon, You Sook Cho, Hee-Bom Moon, Tae-Bum Kim
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/901a25b168e847178eb6cb590ec07f83
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spelling	oai:doaj.org-article:901a25b168e847178eb6cb590ec07f832021-11-18T09:03:18ZInfluence of initial treatment modality on long-term control of chronic idiopathic urticaria.1932-620310.1371/journal.pone.0069345https://doaj.org/article/901a25b168e847178eb6cb590ec07f832013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23935990/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Chronic idiopathic urticaria (CIU) is a common cutaneous disorder but the influence of initial treatment modality on long-term control is not known. The aim of this study was to evaluate clinical features, and the influence of initial treatment modality on long-term control.<h4>Methods and results</h4>641 CIU patients were enrolled from the allergy clinic in a tertiary referral hospital. Disease duration, aggravating factors and treatment modality at each visit were evaluated. Times required to reach a controlled state were analyzed according to initial treatment modality, using Kaplan-Meier survival curves, the Cox proportional-hazards model, and propensity scores. Female to male ratio was 1.7: 1; mean age at onset was 40.5 years. The most common aggravating factors were food (33.5%), stress (31.5%) and fatigue (21.6%). Most patients (82.2%) used H1-antihistamines alone as initial treatment while 17% used a combination treatment with oral corticosteroids. There was no significant difference in the time taken to reach a controlled state between patients treated with single vs multiple H1-antihistamines or between those who received H1-antihistamine monotherapy vs. a combination therapy with oral corticosteroids.<h4>Conclusion</h4>The time required to control CIU is not reduced by use of multiple H1-antihistamines or oral corticosteroids in the initial treatment.Sujeong KimSeunghee BaekBomi ShinSun-young YoonSo Young ParkTaehoon LeeYoon Su LeeYun-Jeong BaeHyouk Soo KwonYou Sook ChoHee-Bom MoonTae-Bum KimPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 7, p e69345 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Sujeong Kim Seunghee Baek Bomi Shin Sun-young Yoon So Young Park Taehoon Lee Yoon Su Lee Yun-Jeong Bae Hyouk Soo Kwon You Sook Cho Hee-Bom Moon Tae-Bum Kim Influence of initial treatment modality on long-term control of chronic idiopathic urticaria.
description	<h4>Background</h4>Chronic idiopathic urticaria (CIU) is a common cutaneous disorder but the influence of initial treatment modality on long-term control is not known. The aim of this study was to evaluate clinical features, and the influence of initial treatment modality on long-term control.<h4>Methods and results</h4>641 CIU patients were enrolled from the allergy clinic in a tertiary referral hospital. Disease duration, aggravating factors and treatment modality at each visit were evaluated. Times required to reach a controlled state were analyzed according to initial treatment modality, using Kaplan-Meier survival curves, the Cox proportional-hazards model, and propensity scores. Female to male ratio was 1.7: 1; mean age at onset was 40.5 years. The most common aggravating factors were food (33.5%), stress (31.5%) and fatigue (21.6%). Most patients (82.2%) used H1-antihistamines alone as initial treatment while 17% used a combination treatment with oral corticosteroids. There was no significant difference in the time taken to reach a controlled state between patients treated with single vs multiple H1-antihistamines or between those who received H1-antihistamine monotherapy vs. a combination therapy with oral corticosteroids.<h4>Conclusion</h4>The time required to control CIU is not reduced by use of multiple H1-antihistamines or oral corticosteroids in the initial treatment.
format	article
author	Sujeong Kim Seunghee Baek Bomi Shin Sun-young Yoon So Young Park Taehoon Lee Yoon Su Lee Yun-Jeong Bae Hyouk Soo Kwon You Sook Cho Hee-Bom Moon Tae-Bum Kim
author_facet	Sujeong Kim Seunghee Baek Bomi Shin Sun-young Yoon So Young Park Taehoon Lee Yoon Su Lee Yun-Jeong Bae Hyouk Soo Kwon You Sook Cho Hee-Bom Moon Tae-Bum Kim
author_sort	Sujeong Kim
title	Influence of initial treatment modality on long-term control of chronic idiopathic urticaria.
title_short	Influence of initial treatment modality on long-term control of chronic idiopathic urticaria.
title_full	Influence of initial treatment modality on long-term control of chronic idiopathic urticaria.
title_fullStr	Influence of initial treatment modality on long-term control of chronic idiopathic urticaria.
title_full_unstemmed	Influence of initial treatment modality on long-term control of chronic idiopathic urticaria.
title_sort	influence of initial treatment modality on long-term control of chronic idiopathic urticaria.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/901a25b168e847178eb6cb590ec07f83
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Influence of initial treatment modality on long-term control of chronic idiopathic urticaria.

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