A metabolic modeling approach reveals promising therapeutic targets and antiviral drugs to combat COVID-19
Abstract In this study we have developed a method based on Flux Balance Analysis to identify human metabolic enzymes which can be targeted for therapeutic intervention against COVID-19. A literature search was carried out in order to identify suitable inhibitors of these enzymes, which were confirme...
Guardado en:
Autores principales: | Fernando Santos-Beneit, Vytautas Raškevičius, Vytenis A. Skeberdis, Sergio Bordel |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/901ee0f78594450698166507df597800 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Transcriptional hallmarks of cancer cell lines reveal an emerging role of branched chain amino acid catabolism
por: Ieva Antanavičiūtė, et al.
Publicado: (2017) -
Development of antiviral therapeutics combating coxsackievirus type B3 infection
por: A. S. Volobueva, et al.
Publicado: (2021) -
Targeting Mitochondria by Plant Secondary Metabolites: A Promising Strategy in Combating Parkinson’s Disease
por: Sajad Fakhri, et al.
Publicado: (2021) -
Genome‐scale metabolic modeling reveals SARS‐CoV‐2‐induced metabolic changes and antiviral targets
por: Kuoyuan Cheng, et al.
Publicado: (2021) -
Hsp90 Inhibition: A Promising Therapeutic Approach for ARSACS
por: Suran Nethisinghe, et al.
Publicado: (2021)