Decline in Stroke Mortality Between 1997 and 2012 by Sex: Ecological Study in Brazilians Aged 15 to 49 Years

Abstract This study aimed to analyse the time trends of stroke mortality between 1997 and 2012 according to sex in Brazilians aged 15 to 49 years. This ecological study used data obtained from the Mortality Information System, which is available from the National Health System Department of Informat...

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Autores principales:	Laércio da Silva Paiva, Fernando Rocha Oliveira, Luiz Vinicius de Alcantara Sousa, Francisco Winter dos Santos Figueiredo, Thiago Hérick de Sá, Fernando Adami
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/90240c8bcf254c089e2317fda8c3ad4c
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spelling	oai:doaj.org-article:90240c8bcf254c089e2317fda8c3ad4c2021-12-02T15:08:20ZDecline in Stroke Mortality Between 1997 and 2012 by Sex: Ecological Study in Brazilians Aged 15 to 49 Years10.1038/s41598-019-39566-82045-2322https://doaj.org/article/90240c8bcf254c089e2317fda8c3ad4c2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-019-39566-8https://doaj.org/toc/2045-2322Abstract This study aimed to analyse the time trends of stroke mortality between 1997 and 2012 according to sex in Brazilians aged 15 to 49 years. This ecological study used data obtained from the Mortality Information System, which is available from the National Health System Department of Informatics - DATASUS and maintained by the Brazilian Ministry of Health. Stroke definition included International Classification of Disease version 10 (ICD-10) codes I60, I61, I63, and I64. Crude and age-standardized mortality rates and respective 95% confidence intervals were estimated per 100,000 inhabitants and stratified by age, region, year, and sex. Linear regression models were used to analyse the time trends with a confidence level of 95%. The statistical program used was Stata 11.0. Between 1997 and 2012, there were 124,866 deaths due to stroke in Brazilians aged 15 to 49 years. There was a decreasing linear trend in stroke mortality among men (β = −0.46, p < 0.001, R2 = 0.95) and women (β = −0.40, p < 0.001, R2 = 0.98) during this period. Overall there was no significant difference in stroke mortality trends by sex, except with respect to the age group of 40 to 49 years where there was a difference in the decrease of stroke mortality between men and women (interaction sex * year: β = 0.238, p = 0.012, R² = 0.96). Mortality rates decrease significantly over time in men and women in the age group 15 to 49 years old, but there is only significant difference in the decrease of rates by sex only in the age group from 40 to 49 years old.Laércio da Silva PaivaFernando Rocha OliveiraLuiz Vinicius de Alcantara SousaFrancisco Winter dos Santos FigueiredoThiago Hérick de SáFernando AdamiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Laércio da Silva Paiva Fernando Rocha Oliveira Luiz Vinicius de Alcantara Sousa Francisco Winter dos Santos Figueiredo Thiago Hérick de Sá Fernando Adami Decline in Stroke Mortality Between 1997 and 2012 by Sex: Ecological Study in Brazilians Aged 15 to 49 Years
description	Abstract This study aimed to analyse the time trends of stroke mortality between 1997 and 2012 according to sex in Brazilians aged 15 to 49 years. This ecological study used data obtained from the Mortality Information System, which is available from the National Health System Department of Informatics - DATASUS and maintained by the Brazilian Ministry of Health. Stroke definition included International Classification of Disease version 10 (ICD-10) codes I60, I61, I63, and I64. Crude and age-standardized mortality rates and respective 95% confidence intervals were estimated per 100,000 inhabitants and stratified by age, region, year, and sex. Linear regression models were used to analyse the time trends with a confidence level of 95%. The statistical program used was Stata 11.0. Between 1997 and 2012, there were 124,866 deaths due to stroke in Brazilians aged 15 to 49 years. There was a decreasing linear trend in stroke mortality among men (β = −0.46, p < 0.001, R2 = 0.95) and women (β = −0.40, p < 0.001, R2 = 0.98) during this period. Overall there was no significant difference in stroke mortality trends by sex, except with respect to the age group of 40 to 49 years where there was a difference in the decrease of stroke mortality between men and women (interaction sex * year: β = 0.238, p = 0.012, R² = 0.96). Mortality rates decrease significantly over time in men and women in the age group 15 to 49 years old, but there is only significant difference in the decrease of rates by sex only in the age group from 40 to 49 years old.
format	article
author	Laércio da Silva Paiva Fernando Rocha Oliveira Luiz Vinicius de Alcantara Sousa Francisco Winter dos Santos Figueiredo Thiago Hérick de Sá Fernando Adami
author_facet	Laércio da Silva Paiva Fernando Rocha Oliveira Luiz Vinicius de Alcantara Sousa Francisco Winter dos Santos Figueiredo Thiago Hérick de Sá Fernando Adami
author_sort	Laércio da Silva Paiva
title	Decline in Stroke Mortality Between 1997 and 2012 by Sex: Ecological Study in Brazilians Aged 15 to 49 Years
title_short	Decline in Stroke Mortality Between 1997 and 2012 by Sex: Ecological Study in Brazilians Aged 15 to 49 Years
title_full	Decline in Stroke Mortality Between 1997 and 2012 by Sex: Ecological Study in Brazilians Aged 15 to 49 Years
title_fullStr	Decline in Stroke Mortality Between 1997 and 2012 by Sex: Ecological Study in Brazilians Aged 15 to 49 Years
title_full_unstemmed	Decline in Stroke Mortality Between 1997 and 2012 by Sex: Ecological Study in Brazilians Aged 15 to 49 Years
title_sort	decline in stroke mortality between 1997 and 2012 by sex: ecological study in brazilians aged 15 to 49 years
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/90240c8bcf254c089e2317fda8c3ad4c
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Decline in Stroke Mortality Between 1997 and 2012 by Sex: Ecological Study in Brazilians Aged 15 to 49 Years

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