Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB

NifB is a radical SAM enzyme involved in the biosynthesis of the Mo-nitrogenase cofactor, which is responsible for the ambient conversion of N2 to NH3. Here, the authors identify and uncover the function of a His43 residue as an essential nitrogen ligand of NifB in cofactor biosynthesis.

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Autores principales:	Lee A. Rettberg, Jarett Wilcoxen, Andrew J. Jasniewski, Chi Chung Lee, Kazuki Tanifuji, Yilin Hu, R. David Britt, Markus W. Ribbe
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/90274eff35004d1e96f2484f0db98a92
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spelling	oai:doaj.org-article:90274eff35004d1e96f2484f0db98a922021-12-02T14:40:52ZIdentity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB10.1038/s41467-020-15627-92041-1723https://doaj.org/article/90274eff35004d1e96f2484f0db98a922020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15627-9https://doaj.org/toc/2041-1723NifB is a radical SAM enzyme involved in the biosynthesis of the Mo-nitrogenase cofactor, which is responsible for the ambient conversion of N2 to NH3. Here, the authors identify and uncover the function of a His43 residue as an essential nitrogen ligand of NifB in cofactor biosynthesis.Lee A. RettbergJarett WilcoxenAndrew J. JasniewskiChi Chung LeeKazuki TanifujiYilin HuR. David BrittMarkus W. RibbeNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lee A. Rettberg Jarett Wilcoxen Andrew J. Jasniewski Chi Chung Lee Kazuki Tanifuji Yilin Hu R. David Britt Markus W. Ribbe Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB
description	NifB is a radical SAM enzyme involved in the biosynthesis of the Mo-nitrogenase cofactor, which is responsible for the ambient conversion of N2 to NH3. Here, the authors identify and uncover the function of a His43 residue as an essential nitrogen ligand of NifB in cofactor biosynthesis.
format	article
author	Lee A. Rettberg Jarett Wilcoxen Andrew J. Jasniewski Chi Chung Lee Kazuki Tanifuji Yilin Hu R. David Britt Markus W. Ribbe
author_facet	Lee A. Rettberg Jarett Wilcoxen Andrew J. Jasniewski Chi Chung Lee Kazuki Tanifuji Yilin Hu R. David Britt Markus W. Ribbe
author_sort	Lee A. Rettberg
title	Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB
title_short	Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB
title_full	Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB
title_fullStr	Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB
title_full_unstemmed	Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB
title_sort	identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein nifb
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/90274eff35004d1e96f2484f0db98a92
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Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB

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