Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function
Infection of a cell with influenza B virus (IBV) often results in cell death and the role of surviving cells in pathogenesis is unclear. Here, Dumm et al. generate a recombinant IBV that activates a host-cell reporter to permanently label infected cells, and show that surviving cells are important t...
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Nature Portfolio
2019
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oai:doaj.org-article:9031272241854e39a95eb61c490bdf382021-12-02T14:38:39ZNon-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function10.1038/s41467-019-08617-z2041-1723https://doaj.org/article/9031272241854e39a95eb61c490bdf382019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08617-zhttps://doaj.org/toc/2041-1723Infection of a cell with influenza B virus (IBV) often results in cell death and the role of surviving cells in pathogenesis is unclear. Here, Dumm et al. generate a recombinant IBV that activates a host-cell reporter to permanently label infected cells, and show that surviving cells are important to preserve epithelial barrier function.Rebekah E. DummJessica K. FiegeBarbara M. WaringChay T. KuoRyan A. LangloisNicholas S. HeatonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
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Science Q Rebekah E. Dumm Jessica K. Fiege Barbara M. Waring Chay T. Kuo Ryan A. Langlois Nicholas S. Heaton Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function |
description |
Infection of a cell with influenza B virus (IBV) often results in cell death and the role of surviving cells in pathogenesis is unclear. Here, Dumm et al. generate a recombinant IBV that activates a host-cell reporter to permanently label infected cells, and show that surviving cells are important to preserve epithelial barrier function. |
format |
article |
author |
Rebekah E. Dumm Jessica K. Fiege Barbara M. Waring Chay T. Kuo Ryan A. Langlois Nicholas S. Heaton |
author_facet |
Rebekah E. Dumm Jessica K. Fiege Barbara M. Waring Chay T. Kuo Ryan A. Langlois Nicholas S. Heaton |
author_sort |
Rebekah E. Dumm |
title |
Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function |
title_short |
Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function |
title_full |
Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function |
title_fullStr |
Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function |
title_full_unstemmed |
Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function |
title_sort |
non-lytic clearance of influenza b virus from infected cells preserves epithelial barrier function |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/9031272241854e39a95eb61c490bdf38 |
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