Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function

Infection of a cell with influenza B virus (IBV) often results in cell death and the role of surviving cells in pathogenesis is unclear. Here, Dumm et al. generate a recombinant IBV that activates a host-cell reporter to permanently label infected cells, and show that surviving cells are important t...

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Autores principales: Rebekah E. Dumm, Jessica K. Fiege, Barbara M. Waring, Chay T. Kuo, Ryan A. Langlois, Nicholas S. Heaton
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9031272241854e39a95eb61c490bdf38
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spelling oai:doaj.org-article:9031272241854e39a95eb61c490bdf382021-12-02T14:38:39ZNon-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function10.1038/s41467-019-08617-z2041-1723https://doaj.org/article/9031272241854e39a95eb61c490bdf382019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08617-zhttps://doaj.org/toc/2041-1723Infection of a cell with influenza B virus (IBV) often results in cell death and the role of surviving cells in pathogenesis is unclear. Here, Dumm et al. generate a recombinant IBV that activates a host-cell reporter to permanently label infected cells, and show that surviving cells are important to preserve epithelial barrier function.Rebekah E. DummJessica K. FiegeBarbara M. WaringChay T. KuoRyan A. LangloisNicholas S. HeatonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Rebekah E. Dumm
Jessica K. Fiege
Barbara M. Waring
Chay T. Kuo
Ryan A. Langlois
Nicholas S. Heaton
Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function
description Infection of a cell with influenza B virus (IBV) often results in cell death and the role of surviving cells in pathogenesis is unclear. Here, Dumm et al. generate a recombinant IBV that activates a host-cell reporter to permanently label infected cells, and show that surviving cells are important to preserve epithelial barrier function.
format article
author Rebekah E. Dumm
Jessica K. Fiege
Barbara M. Waring
Chay T. Kuo
Ryan A. Langlois
Nicholas S. Heaton
author_facet Rebekah E. Dumm
Jessica K. Fiege
Barbara M. Waring
Chay T. Kuo
Ryan A. Langlois
Nicholas S. Heaton
author_sort Rebekah E. Dumm
title Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function
title_short Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function
title_full Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function
title_fullStr Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function
title_full_unstemmed Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function
title_sort non-lytic clearance of influenza b virus from infected cells preserves epithelial barrier function
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/9031272241854e39a95eb61c490bdf38
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