Twelve months of follow-up after intravitreal injection of ranibizumab for the treatment of idiopathic parafoveal telangiectasia

Alexandros Rouvas,1 Panagiotis Malamos,2 Maria Douvali,1 Amalia Ntouraki,1 Nikos N Markomichelakis1 12nd Department of Ophthalmology, Medical School of Athens University, Athens, Greece; 2Department of Ophthalmology, NHS, “G Gennimatas” General Hospital, Athens, Greece Aims: To r...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Rouvas A, Malamos P, Douvali M, Ntouraki A, Markomichelakis NN
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/9038c04193f04c11bfedeed4ddc1fe53
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:9038c04193f04c11bfedeed4ddc1fe53
record_format	dspace
spelling	oai:doaj.org-article:9038c04193f04c11bfedeed4ddc1fe532021-12-02T04:24:15ZTwelve months of follow-up after intravitreal injection of ranibizumab for the treatment of idiopathic parafoveal telangiectasia1177-54671177-5483https://doaj.org/article/9038c04193f04c11bfedeed4ddc1fe532013-07-01T00:00:00Zhttp://www.dovepress.com/twelve-months-of-follow-up-after-intravitreal-injection-of-ranibizumab-a13581https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Alexandros Rouvas,1 Panagiotis Malamos,2 Maria Douvali,1 Amalia Ntouraki,1 Nikos N Markomichelakis1 12nd Department of Ophthalmology, Medical School of Athens University, Athens, Greece; 2Department of Ophthalmology, NHS, “G Gennimatas” General Hospital, Athens, Greece Aims: To report the anatomic and functional outcomes of intravitreal ranibizumab in idiopathic parafoveal telangiectasia (IPT). Material and methods: Four eyes of three patients were included in this interventional case series. One patient (two eyes) had bilateral IPT (type 2) and two patients (two eyes) had unilateral (type 1) IPT. Retreatment was scheduled in case of leakage persistence in combination with visual acuity (VA) deterioration. Fluorescein angiography and optical coherence tomography were performed together with a full ophthalmic examination at baseline, 1, 3, 6, 9, and 12 months after injection. Results: One intravitreal injection of ranibizumab was performed in all four eyes. Complete cessation of leakage was documented postintervention in three eyes and partial cessation in one eye, followed by improvement of best corrected VA in one of them. In all eyes, structural changes of the photoreceptor layer were detected in tomography and were responsible for visual loss, which was in most cases, refractory to the applied therapy. Conclusion: Use of ranibizumab might be efficient in eliminating leakage activity in the macular region in patients with IPT. Nevertheless, improvement in VA was infrequent. Preexisting early photoreceptor alteration in IPT might render such patients unable to improve VA. Keywords: idiopathic parafoveal telangiectasis, intravitreal ranibizumab, fluorescein angiography, high-definition optical coherence tomographyRouvas AMalamos PDouvali MNtouraki AMarkomichelakis NNDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 1357-1362 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Rouvas A Malamos P Douvali M Ntouraki A Markomichelakis NN Twelve months of follow-up after intravitreal injection of ranibizumab for the treatment of idiopathic parafoveal telangiectasia
description	Alexandros Rouvas,1 Panagiotis Malamos,2 Maria Douvali,1 Amalia Ntouraki,1 Nikos N Markomichelakis1 12nd Department of Ophthalmology, Medical School of Athens University, Athens, Greece; 2Department of Ophthalmology, NHS, “G Gennimatas” General Hospital, Athens, Greece Aims: To report the anatomic and functional outcomes of intravitreal ranibizumab in idiopathic parafoveal telangiectasia (IPT). Material and methods: Four eyes of three patients were included in this interventional case series. One patient (two eyes) had bilateral IPT (type 2) and two patients (two eyes) had unilateral (type 1) IPT. Retreatment was scheduled in case of leakage persistence in combination with visual acuity (VA) deterioration. Fluorescein angiography and optical coherence tomography were performed together with a full ophthalmic examination at baseline, 1, 3, 6, 9, and 12 months after injection. Results: One intravitreal injection of ranibizumab was performed in all four eyes. Complete cessation of leakage was documented postintervention in three eyes and partial cessation in one eye, followed by improvement of best corrected VA in one of them. In all eyes, structural changes of the photoreceptor layer were detected in tomography and were responsible for visual loss, which was in most cases, refractory to the applied therapy. Conclusion: Use of ranibizumab might be efficient in eliminating leakage activity in the macular region in patients with IPT. Nevertheless, improvement in VA was infrequent. Preexisting early photoreceptor alteration in IPT might render such patients unable to improve VA. Keywords: idiopathic parafoveal telangiectasis, intravitreal ranibizumab, fluorescein angiography, high-definition optical coherence tomography
format	article
author	Rouvas A Malamos P Douvali M Ntouraki A Markomichelakis NN
author_facet	Rouvas A Malamos P Douvali M Ntouraki A Markomichelakis NN
author_sort	Rouvas A
title	Twelve months of follow-up after intravitreal injection of ranibizumab for the treatment of idiopathic parafoveal telangiectasia
title_short	Twelve months of follow-up after intravitreal injection of ranibizumab for the treatment of idiopathic parafoveal telangiectasia
title_full	Twelve months of follow-up after intravitreal injection of ranibizumab for the treatment of idiopathic parafoveal telangiectasia
title_fullStr	Twelve months of follow-up after intravitreal injection of ranibizumab for the treatment of idiopathic parafoveal telangiectasia
title_full_unstemmed	Twelve months of follow-up after intravitreal injection of ranibizumab for the treatment of idiopathic parafoveal telangiectasia
title_sort	twelve months of follow-up after intravitreal injection of ranibizumab for the treatment of idiopathic parafoveal telangiectasia
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/9038c04193f04c11bfedeed4ddc1fe53
work_keys_str_mv	AT rouvasa twelvemonthsoffollowupafterintravitrealinjectionofranibizumabforthetreatmentofidiopathicparafovealtelangiectasia AT malamosp twelvemonthsoffollowupafterintravitrealinjectionofranibizumabforthetreatmentofidiopathicparafovealtelangiectasia AT douvalim twelvemonthsoffollowupafterintravitrealinjectionofranibizumabforthetreatmentofidiopathicparafovealtelangiectasia AT ntourakia twelvemonthsoffollowupafterintravitrealinjectionofranibizumabforthetreatmentofidiopathicparafovealtelangiectasia AT markomichelakisnn twelvemonthsoffollowupafterintravitrealinjectionofranibizumabforthetreatmentofidiopathicparafovealtelangiectasia
_version_	1718401260971884544

Twelve months of follow-up after intravitreal injection of ranibizumab for the treatment of idiopathic parafoveal telangiectasia

Ejemplares similares