MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair

The mechanics of MMR strand specific excision that begins at a distant ssDNA break are not yet clear. Here the authors have used multiple single molecule imaging techniques to visualize the behavior of MMR components on mismatched DNA substrates and reveal an exonuclease-independent mechanism for E....

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Autores principales:	Jiaquan Liu, Ryanggeun Lee, Brooke M. Britton, James A. London, Keunsang Yang, Jeungphill Hanne, Jong-Bong Lee, Richard Fishel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/903ba956ff58487c9fce0df21e9181e3
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spelling	oai:doaj.org-article:903ba956ff58487c9fce0df21e9181e32021-12-02T15:35:39ZMutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair10.1038/s41467-019-13191-52041-1723https://doaj.org/article/903ba956ff58487c9fce0df21e9181e32019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13191-5https://doaj.org/toc/2041-1723The mechanics of MMR strand specific excision that begins at a distant ssDNA break are not yet clear. Here the authors have used multiple single molecule imaging techniques to visualize the behavior of MMR components on mismatched DNA substrates and reveal an exonuclease-independent mechanism for E.coli MMR.Jiaquan LiuRyanggeun LeeBrooke M. BrittonJames A. LondonKeunsang YangJeungphill HanneJong-Bong LeeRichard FishelNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiaquan Liu Ryanggeun Lee Brooke M. Britton James A. London Keunsang Yang Jeungphill Hanne Jong-Bong Lee Richard Fishel MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair
description	The mechanics of MMR strand specific excision that begins at a distant ssDNA break are not yet clear. Here the authors have used multiple single molecule imaging techniques to visualize the behavior of MMR components on mismatched DNA substrates and reveal an exonuclease-independent mechanism for E.coli MMR.
format	article
author	Jiaquan Liu Ryanggeun Lee Brooke M. Britton James A. London Keunsang Yang Jeungphill Hanne Jong-Bong Lee Richard Fishel
author_facet	Jiaquan Liu Ryanggeun Lee Brooke M. Britton James A. London Keunsang Yang Jeungphill Hanne Jong-Bong Lee Richard Fishel
author_sort	Jiaquan Liu
title	MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair
title_short	MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair
title_full	MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair
title_fullStr	MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair
title_full_unstemmed	MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair
title_sort	mutl sliding clamps coordinate exonuclease-independent escherichia coli mismatch repair
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/903ba956ff58487c9fce0df21e9181e3
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MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair

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