Cortical thickness is differently associated with ALDH2 rs671 polymorphism according to level of amyloid deposition

Abstract Accumulating evidence indicates that amyloid-beta (Aβ) deposition and biogenic aldehyde accumulation contribute to the pathogenesis of neurodegenerative diseases. Human aldehyde dehydrogenase 2 (ALDH2) metabolizes biogenic aldehydes produced in the brain to prevent damage. However, r671G>...

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Autores principales: Yong Hyuk Cho, Heirim Lee, Na-Rae Kim, Jin Wook Choi, Hyun Woong Roh, Jae Ho Ha, Chang Hyung Hong, Sang Won Seo, Seong Hye Choi, Eun-Joo Kim, Byeong C. Kim, Seong Yoon Kim, Jaeyoun Cheong, Bumhee Park, Sang Joon Son
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9047179a77954e6c919236a7bc74aa4e
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