Blocked O-GlcNAc cycling alters mitochondrial morphology, function, and mass

Blocked O-GlcNAc cycling alters mitochondrial morphology, function, and mass

Abstract O-GlcNAcylation is a prevalent form of glycosylation that regulates proteins within the cytosol, nucleus, and mitochondria. The O-GlcNAc modification can affect protein cellular localization, function, and signaling interactions. The specific impact of O-GlcNAcylation on mitochondrial morph...

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Autores principales: Elizabeth O. Akinbiyi, Lara K. Abramowitz, Brianna L. Bauer, Maria S. K. Stoll, Charles L. Hoppel, Chao-Pin Hsiao, John A. Hanover, Jason A. Mears
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/9048e2672c6344cea6e502b9ebc484a0
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