Cervical Carcinoma: Oncobiology and Biomarkers

Cervical cancer is one of the most common types of carcinomas causing morbidity and mortality in women in all countries of the world. At the moment, the oncology, oncobiology, and oncomorphology of cervical cancer are characterized by the accumulation of new information; various molecular biological...

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Autores principales:	Larisa V. Volkova, Alexander I. Pashov, Nadezhda N. Omelchuk
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	carcinoma of the cervix cervical carcinogenesis biomarkers immunohistochemistry Biology (General) QH301-705.5 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/9049e4a5cbf6405083b4b4d17931fa4d
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spelling	oai:doaj.org-article:9049e4a5cbf6405083b4b4d17931fa4d2021-11-25T17:57:58ZCervical Carcinoma: Oncobiology and Biomarkers10.3390/ijms2222125711422-00671661-6596https://doaj.org/article/9049e4a5cbf6405083b4b4d17931fa4d2021-11-01T00:00:00Zhttps://www.mdpi.com/1422-0067/22/22/12571https://doaj.org/toc/1661-6596https://doaj.org/toc/1422-0067Cervical cancer is one of the most common types of carcinomas causing morbidity and mortality in women in all countries of the world. At the moment, the oncology, oncobiology, and oncomorphology of cervical cancer are characterized by the accumulation of new information; various molecular biological, genetic, and immunohistochemical methods of investigation of the mechanisms of cervical carcinogenesis are tested and applied; targeted antitumour drugs and diagnostic, prognostic, and predictive biomarkers are being searched for. Many issues of the etiopathogenesis of cervical cancer have not been sufficiently studied, and the role of many biomarkers characterizing various stages of cervical carcinogenesis remains unclear. Therefore, the target of this review is to systematize and understand several problems in the pathogenesis of cervical cancer and to evaluate the significance and role of biomarkers in cervical carcinogenesis.Larisa V. VolkovaAlexander I. PashovNadezhda N. OmelchukMDPI AGarticlecarcinoma of the cervixcervical carcinogenesisbiomarkersimmunohistochemistryBiology (General)QH301-705.5ChemistryQD1-999ENInternational Journal of Molecular Sciences, Vol 22, Iss 12571, p 12571 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	carcinoma of the cervix cervical carcinogenesis biomarkers immunohistochemistry Biology (General) QH301-705.5 Chemistry QD1-999
spellingShingle	carcinoma of the cervix cervical carcinogenesis biomarkers immunohistochemistry Biology (General) QH301-705.5 Chemistry QD1-999 Larisa V. Volkova Alexander I. Pashov Nadezhda N. Omelchuk Cervical Carcinoma: Oncobiology and Biomarkers
description	Cervical cancer is one of the most common types of carcinomas causing morbidity and mortality in women in all countries of the world. At the moment, the oncology, oncobiology, and oncomorphology of cervical cancer are characterized by the accumulation of new information; various molecular biological, genetic, and immunohistochemical methods of investigation of the mechanisms of cervical carcinogenesis are tested and applied; targeted antitumour drugs and diagnostic, prognostic, and predictive biomarkers are being searched for. Many issues of the etiopathogenesis of cervical cancer have not been sufficiently studied, and the role of many biomarkers characterizing various stages of cervical carcinogenesis remains unclear. Therefore, the target of this review is to systematize and understand several problems in the pathogenesis of cervical cancer and to evaluate the significance and role of biomarkers in cervical carcinogenesis.
format	article
author	Larisa V. Volkova Alexander I. Pashov Nadezhda N. Omelchuk
author_facet	Larisa V. Volkova Alexander I. Pashov Nadezhda N. Omelchuk
author_sort	Larisa V. Volkova
title	Cervical Carcinoma: Oncobiology and Biomarkers
title_short	Cervical Carcinoma: Oncobiology and Biomarkers
title_full	Cervical Carcinoma: Oncobiology and Biomarkers
title_fullStr	Cervical Carcinoma: Oncobiology and Biomarkers
title_full_unstemmed	Cervical Carcinoma: Oncobiology and Biomarkers
title_sort	cervical carcinoma: oncobiology and biomarkers
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/9049e4a5cbf6405083b4b4d17931fa4d
work_keys_str_mv	AT larisavvolkova cervicalcarcinomaoncobiologyandbiomarkers AT alexanderipashov cervicalcarcinomaoncobiologyandbiomarkers AT nadezhdanomelchuk cervicalcarcinomaoncobiologyandbiomarkers
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Cervical Carcinoma: Oncobiology and Biomarkers

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