Pulmonary histopathology in fatal paraquat poisoning

Paraquat is a potent herbicide widely used in the Indian agriculture industry. Human fatality due to paraquat poisoning is not uncommon in this country. The primary effect of paraquat is on the lungs, and the resultant pulmonary damage leads to the patient’s demise. There is a high mortality rate i...

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Autores principales:	Senthil Kumar, Shikha Gupta, Yogender Singh Bansal, Amanjit Bal, Pulkit Rastogi, Valliappan Muthu, Vanshika Arora
Formato:	article
Lenguaje:	EN
Publicado:	University of São Paulo 2021
Materias:	Paraquat Acute toxicity Autopsy Histology Lung injury Medicine R Internal medicine RC31-1245
Acceso en línea:	https://doaj.org/article/9050cd9f34f04deb818f92b1da23c2c4
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id	oai:doaj.org-article:9050cd9f34f04deb818f92b1da23c2c4
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spelling	oai:doaj.org-article:9050cd9f34f04deb818f92b1da23c2c42021-11-24T04:10:38ZPulmonary histopathology in fatal paraquat poisoning2236-1960https://doaj.org/article/9050cd9f34f04deb818f92b1da23c2c42021-11-01T00:00:00Zhttps://www.revistas.usp.br/autopsy/article/view/192810https://doaj.org/toc/2236-1960 Paraquat is a potent herbicide widely used in the Indian agriculture industry. Human fatality due to paraquat poisoning is not uncommon in this country. The primary effect of paraquat is on the lungs, and the resultant pulmonary damage leads to the patient’s demise. There is a high mortality rate in paraquat poisoning as the treatment is usually supportive with no known antidote. There are limited human studies that have observed the histopathological changes in lungs in paraquat poisoning. The authors have discussed the time-related histopathological changes in lungs in paraquat poisoning on autopsy subjects. The role of anticoagulants and fibrinolytic agents in the treatment of this poisoning has also been discussed. Senthil KumarShikha GuptaYogender Singh BansalAmanjit BalPulkit RastogiValliappan MuthuVanshika AroraUniversity of São PauloarticleParaquatAcute toxicityAutopsyHistologyLung injuryMedicineRInternal medicineRC31-1245ENAutopsy and Case Reports, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Paraquat Acute toxicity Autopsy Histology Lung injury Medicine R Internal medicine RC31-1245
spellingShingle	Paraquat Acute toxicity Autopsy Histology Lung injury Medicine R Internal medicine RC31-1245 Senthil Kumar Shikha Gupta Yogender Singh Bansal Amanjit Bal Pulkit Rastogi Valliappan Muthu Vanshika Arora Pulmonary histopathology in fatal paraquat poisoning
description	Paraquat is a potent herbicide widely used in the Indian agriculture industry. Human fatality due to paraquat poisoning is not uncommon in this country. The primary effect of paraquat is on the lungs, and the resultant pulmonary damage leads to the patient’s demise. There is a high mortality rate in paraquat poisoning as the treatment is usually supportive with no known antidote. There are limited human studies that have observed the histopathological changes in lungs in paraquat poisoning. The authors have discussed the time-related histopathological changes in lungs in paraquat poisoning on autopsy subjects. The role of anticoagulants and fibrinolytic agents in the treatment of this poisoning has also been discussed.
format	article
author	Senthil Kumar Shikha Gupta Yogender Singh Bansal Amanjit Bal Pulkit Rastogi Valliappan Muthu Vanshika Arora
author_facet	Senthil Kumar Shikha Gupta Yogender Singh Bansal Amanjit Bal Pulkit Rastogi Valliappan Muthu Vanshika Arora
author_sort	Senthil Kumar
title	Pulmonary histopathology in fatal paraquat poisoning
title_short	Pulmonary histopathology in fatal paraquat poisoning
title_full	Pulmonary histopathology in fatal paraquat poisoning
title_fullStr	Pulmonary histopathology in fatal paraquat poisoning
title_full_unstemmed	Pulmonary histopathology in fatal paraquat poisoning
title_sort	pulmonary histopathology in fatal paraquat poisoning
publisher	University of São Paulo
publishDate	2021
url	https://doaj.org/article/9050cd9f34f04deb818f92b1da23c2c4
work_keys_str_mv	AT senthilkumar pulmonaryhistopathologyinfatalparaquatpoisoning AT shikhagupta pulmonaryhistopathologyinfatalparaquatpoisoning AT yogendersinghbansal pulmonaryhistopathologyinfatalparaquatpoisoning AT amanjitbal pulmonaryhistopathologyinfatalparaquatpoisoning AT pulkitrastogi pulmonaryhistopathologyinfatalparaquatpoisoning AT valliappanmuthu pulmonaryhistopathologyinfatalparaquatpoisoning AT vanshikaarora pulmonaryhistopathologyinfatalparaquatpoisoning
_version_	1718416047681306624

Pulmonary histopathology in fatal paraquat poisoning

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