Dual function of histone H3 lysine 36 methyltransferase ASH1 in regulation of Hox gene expression.

Dual function of histone H3 lysine 36 methyltransferase ASH1 in regulation of Hox gene expression.

Hox genes play important roles in haematopoietic development in mammals. ASH1 is a member of the trithorax group (trxG) that is required for proper expression of Hox genes and is preferentially expressed in haematopoietic stem cells. We have recently reported that ASH1 methylates histone H3 at lysin...

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Autores principales: Yujiro Tanaka, Koji Kawahashi, Zen-Ichiro Katagiri, Yasuhiro Nakayama, Milind Mahajan, Dimitris Kioussis
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/9055b1051b904f7187a6e8be96043fa6
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