Optic disc size and progression of visual field damage in patients with normal-tension glaucoma

Fukuko Hayamizu, Yoshio Yamazaki, Takako Nakagami, Kenji MizukiDepartment of Ophthalmology, Division of Visual Science, Nihon University School of Medicine, Tokyo, JapanPurpose: Our goal was to evaluate the influence of optic disc size on the progression of visual field damage in patients with norma...

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Autores principales:	Hayamizu F, Yamazaki Y, Nakagami T, Mizuki K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/905c67a5099f46039a7d06da51bcec53
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spelling	oai:doaj.org-article:905c67a5099f46039a7d06da51bcec532021-12-02T02:11:57ZOptic disc size and progression of visual field damage in patients with normal-tension glaucoma1177-54671177-5483https://doaj.org/article/905c67a5099f46039a7d06da51bcec532013-05-01T00:00:00Zhttp://www.dovepress.com/optic-disc-size-and-progression-of-visual-field-damage-in-patients-wit-a12935https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Fukuko Hayamizu, Yoshio Yamazaki, Takako Nakagami, Kenji MizukiDepartment of Ophthalmology, Division of Visual Science, Nihon University School of Medicine, Tokyo, JapanPurpose: Our goal was to evaluate the influence of optic disc size on the progression of visual field damage in patients with normal-tension glaucoma (NTG).Subjects and methods: Eighty-two eyes of 82 NTG patients who had been receiving topical antiglaucoma medications and followed-up for more than 4 years were enrolled in this study. The patients were allocated to two groups, according to the mean size of their optic discs. The data were analyzed using regression analysis, based on the Cox proportional hazard model.Results: The probability of visual field stability was significantly lower in eyes with large discs than in those with small discs (log rank test, P = 0.007). Progression of visual field damage was significantly associated with the optic disc area (hazard ratio [HR]: 1.812, P = 0.018), occurrence of disc hemorrhage (HR: 2.116, P = 0.028), and intraocular pressure reduction ratio (HR: 0.957, P = 0.014).Conclusion: The optic disc area correlates with progression of visual field damage in patients with NTG.Keywords: Cox proportional hazards model, disc hemorrhage, disc size, intraocular pressure, Kaplan–Meier life-table analysisHayamizu FYamazaki YNakagami TMizuki KDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 807-813 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Hayamizu F Yamazaki Y Nakagami T Mizuki K Optic disc size and progression of visual field damage in patients with normal-tension glaucoma
description	Fukuko Hayamizu, Yoshio Yamazaki, Takako Nakagami, Kenji MizukiDepartment of Ophthalmology, Division of Visual Science, Nihon University School of Medicine, Tokyo, JapanPurpose: Our goal was to evaluate the influence of optic disc size on the progression of visual field damage in patients with normal-tension glaucoma (NTG).Subjects and methods: Eighty-two eyes of 82 NTG patients who had been receiving topical antiglaucoma medications and followed-up for more than 4 years were enrolled in this study. The patients were allocated to two groups, according to the mean size of their optic discs. The data were analyzed using regression analysis, based on the Cox proportional hazard model.Results: The probability of visual field stability was significantly lower in eyes with large discs than in those with small discs (log rank test, P = 0.007). Progression of visual field damage was significantly associated with the optic disc area (hazard ratio [HR]: 1.812, P = 0.018), occurrence of disc hemorrhage (HR: 2.116, P = 0.028), and intraocular pressure reduction ratio (HR: 0.957, P = 0.014).Conclusion: The optic disc area correlates with progression of visual field damage in patients with NTG.Keywords: Cox proportional hazards model, disc hemorrhage, disc size, intraocular pressure, Kaplan–Meier life-table analysis
format	article
author	Hayamizu F Yamazaki Y Nakagami T Mizuki K
author_facet	Hayamizu F Yamazaki Y Nakagami T Mizuki K
author_sort	Hayamizu F
title	Optic disc size and progression of visual field damage in patients with normal-tension glaucoma
title_short	Optic disc size and progression of visual field damage in patients with normal-tension glaucoma
title_full	Optic disc size and progression of visual field damage in patients with normal-tension glaucoma
title_fullStr	Optic disc size and progression of visual field damage in patients with normal-tension glaucoma
title_full_unstemmed	Optic disc size and progression of visual field damage in patients with normal-tension glaucoma
title_sort	optic disc size and progression of visual field damage in patients with normal-tension glaucoma
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/905c67a5099f46039a7d06da51bcec53
work_keys_str_mv	AT hayamizuf opticdiscsizeandprogressionofvisualfielddamageinpatientswithnormaltensionglaucoma AT yamazakiy opticdiscsizeandprogressionofvisualfielddamageinpatientswithnormaltensionglaucoma AT nakagamit opticdiscsizeandprogressionofvisualfielddamageinpatientswithnormaltensionglaucoma AT mizukik opticdiscsizeandprogressionofvisualfielddamageinpatientswithnormaltensionglaucoma
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Optic disc size and progression of visual field damage in patients with normal-tension glaucoma

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