Comparison of Seminal Plasma Total Antioxidant Capacity in Human Semen with Hyperviscosity and Non-Hyperviscosity

BACKGROUND AND OBJECTIVE: Several factors have influence on sperm fertilization, between them semen hyperviscosity is one of the idiopathic factors involved in sperm viability and function deficiency. Probably, decrease in human seminal antioxidants is one of the negative effects of hyperviscosity o...

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Autores principales:	E Tahmasbpour Marzony, GH.A Jorsaraei, M Pouramir, A Hosseinzadeh Colagar
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2012
Materias:	semen hyperviscosity seminal antioxidants infertility Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/905db058a31140dbabaea826764f9304
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spelling	oai:doaj.org-article:905db058a31140dbabaea826764f93042021-11-10T08:53:33ZComparison of Seminal Plasma Total Antioxidant Capacity in Human Semen with Hyperviscosity and Non-Hyperviscosity1561-41072251-7170https://doaj.org/article/905db058a31140dbabaea826764f93042012-11-01T00:00:00Zhttp://jbums.org/article-1-4238-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Several factors have influence on sperm fertilization, between them semen hyperviscosity is one of the idiopathic factors involved in sperm viability and function deficiency. Probably, decrease in human seminal antioxidants is one of the negative effects of hyperviscosity on sperm function. The aim of this study was to compare the total antioxidant activity (TAC) in seminal plasma of infertile patients with hyperviscosity and non- hyperviscosity.METHODS: In this cross sectional study, 47 semen samples were provided from infertile patients with hyperviscosity (n=22) and without hyperviscosity (n=25) at Fatemeh Zahra Infertility and Health Reproductive Research Center. After determine the semen hyperviscosity by measuring the length of the thread on withdrawal of the rod, sperm parameters (volume, sperm counts, motility and normal morphology) were evaluated on microscopic examination. TAC was measured in all samples by FRAP method and compared.FINDINGS: The mean of sperm parameters including: counts (29.32 ± 25.35), motility (30.95 ± 19.11) and normal morphology (4.23 ± 2.5) in patients with hyperviscosity were significantly lower than those in non-hyperviscosity patients (counts 46.80 ± 26.29, motility (52.8 ± 15.41) and normal morphology (7.56 ± 3.16)) (p<0.02, p<0.001 and p<0.001, respectively). The mean of TAC in seminal plasma of non- hyperviscosity patients (1710.31 ± 458.67µmol/l) was significantly higher than that of hyperviscosity group (1230.25 ± 352 µmol/l) (p<0.01). CONCLUSION: Our results showed that there is a positive significant correlation between TAC and sperm parameters quality. Decrease in TAC concentration in seminal plasma of patients with hyperviscosity is one of the probability mechanisms for sperm parameters abnormality.E Tahmasbpour Marzony,GH.A Jorsaraei,M Pouramir,A Hosseinzadeh ColagarBabol University of Medical Sciencesarticlesemen hyperviscosityseminal antioxidantsinfertilityMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 14, Iss 6, Pp 39-44 (2012)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	semen hyperviscosity seminal antioxidants infertility Medicine R Medicine (General) R5-920
spellingShingle	semen hyperviscosity seminal antioxidants infertility Medicine R Medicine (General) R5-920 E Tahmasbpour Marzony, GH.A Jorsaraei, M Pouramir, A Hosseinzadeh Colagar Comparison of Seminal Plasma Total Antioxidant Capacity in Human Semen with Hyperviscosity and Non-Hyperviscosity
description	BACKGROUND AND OBJECTIVE: Several factors have influence on sperm fertilization, between them semen hyperviscosity is one of the idiopathic factors involved in sperm viability and function deficiency. Probably, decrease in human seminal antioxidants is one of the negative effects of hyperviscosity on sperm function. The aim of this study was to compare the total antioxidant activity (TAC) in seminal plasma of infertile patients with hyperviscosity and non- hyperviscosity.METHODS: In this cross sectional study, 47 semen samples were provided from infertile patients with hyperviscosity (n=22) and without hyperviscosity (n=25) at Fatemeh Zahra Infertility and Health Reproductive Research Center. After determine the semen hyperviscosity by measuring the length of the thread on withdrawal of the rod, sperm parameters (volume, sperm counts, motility and normal morphology) were evaluated on microscopic examination. TAC was measured in all samples by FRAP method and compared.FINDINGS: The mean of sperm parameters including: counts (29.32 ± 25.35), motility (30.95 ± 19.11) and normal morphology (4.23 ± 2.5) in patients with hyperviscosity were significantly lower than those in non-hyperviscosity patients (counts 46.80 ± 26.29, motility (52.8 ± 15.41) and normal morphology (7.56 ± 3.16)) (p<0.02, p<0.001 and p<0.001, respectively). The mean of TAC in seminal plasma of non- hyperviscosity patients (1710.31 ± 458.67µmol/l) was significantly higher than that of hyperviscosity group (1230.25 ± 352 µmol/l) (p<0.01). CONCLUSION: Our results showed that there is a positive significant correlation between TAC and sperm parameters quality. Decrease in TAC concentration in seminal plasma of patients with hyperviscosity is one of the probability mechanisms for sperm parameters abnormality.
format	article
author	E Tahmasbpour Marzony, GH.A Jorsaraei, M Pouramir, A Hosseinzadeh Colagar
author_facet	E Tahmasbpour Marzony, GH.A Jorsaraei, M Pouramir, A Hosseinzadeh Colagar
author_sort	E Tahmasbpour Marzony,
title	Comparison of Seminal Plasma Total Antioxidant Capacity in Human Semen with Hyperviscosity and Non-Hyperviscosity
title_short	Comparison of Seminal Plasma Total Antioxidant Capacity in Human Semen with Hyperviscosity and Non-Hyperviscosity
title_full	Comparison of Seminal Plasma Total Antioxidant Capacity in Human Semen with Hyperviscosity and Non-Hyperviscosity
title_fullStr	Comparison of Seminal Plasma Total Antioxidant Capacity in Human Semen with Hyperviscosity and Non-Hyperviscosity
title_full_unstemmed	Comparison of Seminal Plasma Total Antioxidant Capacity in Human Semen with Hyperviscosity and Non-Hyperviscosity
title_sort	comparison of seminal plasma total antioxidant capacity in human semen with hyperviscosity and non-hyperviscosity
publisher	Babol University of Medical Sciences
publishDate	2012
url	https://doaj.org/article/905db058a31140dbabaea826764f9304
work_keys_str_mv	AT etahmasbpourmarzony comparisonofseminalplasmatotalantioxidantcapacityinhumansemenwithhyperviscosityandnonhyperviscosity AT ghajorsaraei comparisonofseminalplasmatotalantioxidantcapacityinhumansemenwithhyperviscosityandnonhyperviscosity AT mpouramir comparisonofseminalplasmatotalantioxidantcapacityinhumansemenwithhyperviscosityandnonhyperviscosity AT ahosseinzadehcolagar comparisonofseminalplasmatotalantioxidantcapacityinhumansemenwithhyperviscosityandnonhyperviscosity
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Comparison of Seminal Plasma Total Antioxidant Capacity in Human Semen with Hyperviscosity and Non-Hyperviscosity

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