The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway
As a ubiquitin sensor and a signal-transducing adaptor, p62 is crucial for NF-κB activation, which involves the ubiquitin machinery in diverse contexts. However, whether p62 is required for EBV LMP1 activation of NF-κB is an open question.
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American Society for Microbiology
2021
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oai:doaj.org-article:9062215602b446458b173e626e8fb19d2021-11-03T21:52:35ZThe Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway2150-751110.1128/mBio.01097-21https://doaj.org/article/9062215602b446458b173e626e8fb19d2021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01097-21https://doaj.org/toc/2150-7511 As a ubiquitin sensor and a signal-transducing adaptor, p62 is crucial for NF-κB activation, which involves the ubiquitin machinery in diverse contexts. However, whether p62 is required for EBV LMP1 activation of NF-κB is an open question.Ling WangMary E. A. HowellAyrianna Sparks-WallaceJuan ZhaoCulton R. HensleyCamri A. NicksicShanna R. HorneKaylea B. MohrJonathan P. MoormanZhi Q. YaoShunbin NingAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Microbiology QR1-502 |
| spellingShingle |
Microbiology QR1-502 Ling Wang Mary E. A. Howell Ayrianna Sparks-Wallace Juan Zhao Culton R. Hensley Camri A. Nicksic Shanna R. Horne Kaylea B. Mohr Jonathan P. Moorman Zhi Q. Yao Shunbin Ning The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway |
| description |
As a ubiquitin sensor and a signal-transducing adaptor, p62 is crucial for NF-κB activation, which involves the ubiquitin machinery in diverse contexts. However, whether p62 is required for EBV LMP1 activation of NF-κB is an open question. |
| format |
article |
| author |
Ling Wang Mary E. A. Howell Ayrianna Sparks-Wallace Juan Zhao Culton R. Hensley Camri A. Nicksic Shanna R. Horne Kaylea B. Mohr Jonathan P. Moorman Zhi Q. Yao Shunbin Ning |
| author_facet |
Ling Wang Mary E. A. Howell Ayrianna Sparks-Wallace Juan Zhao Culton R. Hensley Camri A. Nicksic Shanna R. Horne Kaylea B. Mohr Jonathan P. Moorman Zhi Q. Yao Shunbin Ning |
| author_sort |
Ling Wang |
| title |
The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway |
| title_short |
The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway |
| title_full |
The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway |
| title_fullStr |
The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway |
| title_full_unstemmed |
The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway |
| title_sort |
ubiquitin sensor and adaptor protein p62 mediates signal transduction of a viral oncogenic pathway |
| publisher |
American Society for Microbiology |
| publishDate |
2021 |
| url |
https://doaj.org/article/9062215602b446458b173e626e8fb19d |
| work_keys_str_mv |
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1718445344690274304 |