Structure-Informed Design of an Enzymatically Inactive Vaccine Component for Group A <italic toggle="yes">Streptococcus</italic>
ABSTRACT Streptococcus pyogenes (group A Streptococcus [GAS]) causes ~700 million human infections/year, resulting in >500,000 deaths. There is no commercial GAS vaccine available. The GAS surface protein arginine deiminase (ADI) protects mice against a lethal challenge. ADI is an enzyme that con...
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| Main Authors: | , , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2013
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| Subjects: | |
| Online Access: | https://doaj.org/article/90669fba22484c2091bf8b72cdcee539 |
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