Estimating utility weights and quality-adjusted life year loss for colorectal cancer-related health states in Korea

Abstract We aimed to assess utility weight of health states associated with colorectal cancer (CRC) that reflect the societal preference of the Korean population and to estimate the quality-adjusted life year (QALY) loss with CRC. We recruited 607 individuals from the Korean population; they were su...

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Autores principales:	Jin Yong Lee, Minsu Ock, Min-Woo Jo, Woo-Seung Son, Hyeon-Jeong Lee, Seon-Ha Kim, Hyun Joo Kim, Jong Lyul Lee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/906fb9cf798f4183a10a62aa9249176c
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spelling	oai:doaj.org-article:906fb9cf798f4183a10a62aa9249176c2021-12-02T11:40:53ZEstimating utility weights and quality-adjusted life year loss for colorectal cancer-related health states in Korea10.1038/s41598-017-06004-62045-2322https://doaj.org/article/906fb9cf798f4183a10a62aa9249176c2017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-06004-6https://doaj.org/toc/2045-2322Abstract We aimed to assess utility weight of health states associated with colorectal cancer (CRC) that reflect the societal preference of the Korean population and to estimate the quality-adjusted life year (QALY) loss with CRC. We recruited 607 individuals from the Korean population; they were surveyed via face-to-face computer-assisted interviews. The participants evaluated each CRC-associated health state using standard gamble. Utility weight for each health state was calculated as the possibility of full health restoration. Moreover, we estimated total QALY loss due to CRC in Korean individuals aged ≥30 years in 2013. To calculate QALY due to morbidity, we yielded utility weights and used epidemiologic data of CRC on severity from the National Cancer Control Institute. QALY loss due to mortality was calculated using mortality of CRC and life expectancy data from the Korean Statistical Information Service. The highest and lowest utility weights were assigned to “adenomatous polyps” and “metastatic colon cancer”, respectively. Total QALY loss due to CRC in Korea was 173,662; these patients were more likely to be men or be included in the 70–74-year age group. These utility weights may be useful for conducting cost-utility studies of cancer screening for CRC and for measuring disease burden with QALY.Jin Yong LeeMinsu OckMin-Woo JoWoo-Seung SonHyeon-Jeong LeeSeon-Ha KimHyun Joo KimJong Lyul LeeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Jin Yong Lee Minsu Ock Min-Woo Jo Woo-Seung Son Hyeon-Jeong Lee Seon-Ha Kim Hyun Joo Kim Jong Lyul Lee Estimating utility weights and quality-adjusted life year loss for colorectal cancer-related health states in Korea
description	Abstract We aimed to assess utility weight of health states associated with colorectal cancer (CRC) that reflect the societal preference of the Korean population and to estimate the quality-adjusted life year (QALY) loss with CRC. We recruited 607 individuals from the Korean population; they were surveyed via face-to-face computer-assisted interviews. The participants evaluated each CRC-associated health state using standard gamble. Utility weight for each health state was calculated as the possibility of full health restoration. Moreover, we estimated total QALY loss due to CRC in Korean individuals aged ≥30 years in 2013. To calculate QALY due to morbidity, we yielded utility weights and used epidemiologic data of CRC on severity from the National Cancer Control Institute. QALY loss due to mortality was calculated using mortality of CRC and life expectancy data from the Korean Statistical Information Service. The highest and lowest utility weights were assigned to “adenomatous polyps” and “metastatic colon cancer”, respectively. Total QALY loss due to CRC in Korea was 173,662; these patients were more likely to be men or be included in the 70–74-year age group. These utility weights may be useful for conducting cost-utility studies of cancer screening for CRC and for measuring disease burden with QALY.
format	article
author	Jin Yong Lee Minsu Ock Min-Woo Jo Woo-Seung Son Hyeon-Jeong Lee Seon-Ha Kim Hyun Joo Kim Jong Lyul Lee
author_facet	Jin Yong Lee Minsu Ock Min-Woo Jo Woo-Seung Son Hyeon-Jeong Lee Seon-Ha Kim Hyun Joo Kim Jong Lyul Lee
author_sort	Jin Yong Lee
title	Estimating utility weights and quality-adjusted life year loss for colorectal cancer-related health states in Korea
title_short	Estimating utility weights and quality-adjusted life year loss for colorectal cancer-related health states in Korea
title_full	Estimating utility weights and quality-adjusted life year loss for colorectal cancer-related health states in Korea
title_fullStr	Estimating utility weights and quality-adjusted life year loss for colorectal cancer-related health states in Korea
title_full_unstemmed	Estimating utility weights and quality-adjusted life year loss for colorectal cancer-related health states in Korea
title_sort	estimating utility weights and quality-adjusted life year loss for colorectal cancer-related health states in korea
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/906fb9cf798f4183a10a62aa9249176c
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Estimating utility weights and quality-adjusted life year loss for colorectal cancer-related health states in Korea

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