Herpes simplex virus-1 KOS-63 strain is virulent and causes titer-dependent corneal nerve damage and keratitis

Abstract To investigate the acute clinical, immunological, and corneal nerve changes following corneal HSV-1 KOS-63 strain inoculation. Corneas of C57BL/6 mice were inoculated with either low dose (Ld) or high dose (Hd) HSV-1 KOS-63 or culture medium. Clinical evaluation was conducted up to 7 days p...

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Autores principales: Hamid-Reza Moein, Victor G. Sendra, Arsia Jamali, Ahmad Kheirkhah, Deshea L. Harris, Pedram Hamrah
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9070c8e29edd4f1ab5b45e8ae1b6d68c
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