Quantitative refractive index distribution of single cell by combining phase-shifting interferometry and AFM imaging

Abstract Cell refractive index, an intrinsic optical parameter, is closely correlated with the intracellular mass and concentration. By combining optical phase-shifting interferometry (PSI) and atomic force microscope (AFM) imaging, we constructed a label free, non-invasive and quantitative refracti...

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Autores principales: Qinnan Zhang, Liyun Zhong, Ping Tang, Yingjie Yuan, Shengde Liu, Jindong Tian, Xiaoxu Lu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/9076c89ffbff4fce880c580fedaa510c
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