SARS-CoV-2 seroprevalence in Mongolia: Results from a national population survey

Summary: Background: With the global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in early 2020, Mongolia implemented rapid emergency measures and did not report local transmission until November 2020. We conducted a national seroprevalence survey to monitor the burden of...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Battogtokh Chimeddorj, Undram Mandakh, Linh-Vi Le, Batzorig Bayartsogt, Zolzaya Deleg, Oyunsuren Enebish, Oyunbaatar Altanbayar, Battur Magvan, Anuujin Gantumur, Otgonjargal Byambaa, Gerelmaa Enebish, Bat-Erdene Saindoo, Mandakhnaran Davaadorj, Avarzed Amgalanbaatar, Khangai Enkhtugs, Usukhbayar Munkhbayar, Batkhuu Bayanjargal, Tuyajargal Badamsambuu, Myagmartseren Dashtseren, Zolmunkh Narmandakh, Khongorzul Togoo, Enkh-Amar Boldbaatar, Ariunzaya Bat-Erdene, Yerkyebulan Mukhtar, Oyu-Erdene Shagdarsuren, Mandukhai Ganbat, Ochbadrakh Batjargal, Bayasgalantai Bavuusuren, Batzaya Batchuluun, Gereltsetseg Zulmunkh, Ganbaatar Byambatsogt, Khurelbaatar Nyamdavaa, Tserendagva Dalkh, Damdindorj Boldbaatar, Tuvshinjargal Tseren, Darambazar Gantulga, Otgonbayar Damdinbazar, Byambasuren Vanchin, Lorenzo Subissi, Isabel Bergeri, Davaalkham Dambadarjaa, Nymadawa Pagbajabyn, Gregory Greif, Ryenchindorj Erkhembayar
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	SARS-CoV-2 COVID-19 Pandemics Seroepidemiological studies Mongolia Seroprevalence Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/908f608d11284685ab8ab11de81d0e0b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:908f608d11284685ab8ab11de81d0e0b
record_format	dspace
spelling	oai:doaj.org-article:908f608d11284685ab8ab11de81d0e0b2021-11-24T04:34:52ZSARS-CoV-2 seroprevalence in Mongolia: Results from a national population survey2666-606510.1016/j.lanwpc.2021.100317https://doaj.org/article/908f608d11284685ab8ab11de81d0e0b2021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2666606521002261https://doaj.org/toc/2666-6065Summary: Background: With the global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in early 2020, Mongolia implemented rapid emergency measures and did not report local transmission until November 2020. We conducted a national seroprevalence survey to monitor the burden of SARS-CoV-2 in Mongolia in the months surrounding the first local transmission. Methods: During October-December 2020, participants were randomly selected using age stratification and invited for interviews and blood samples at local primary health centres. We screened for total SARS-CoV-2 antibodies, followed by two-step quantitative SARS-CoV-2 IgG serology tests for positive samples. Weighted and test-adjusted seroprevalences were estimated. We used chi-square, Fisher's exact and other tests to identify variables associated with seropositivity. Findings: A total of 5000 subjects were enrolled. We detected SARS-CoV-2 IgG antibodies in 72 samples. Crude seroprevalence of SARS-CoV-2 antibodies was 1·44% (95%CI,1·21-1·67). Population weighted and test-adjusted seroprevalences were 1·36% (95%CI,1·11-1·63) and 1·45% (95%CI,1·11-1·63), respectively. Age, sex, geographical, and occupational factors were not associated with seropositivity (p>0·05). Symptoms and signs within past 3 months and seropositivity were not associated at the time of the survey (p>0·05). Interpretation: SARS-CoV-2 seroprevalence in Mongolia was low in the first year of the pandemic potentially due to strong public health measures, including border restrictions, educational facilities closure, earlier adoption of mask-wearing and others. Our findings suggest large-scale community transmission could not have occurred up to November 2020 in Mongolia. Additional serosurveys are needed to monitor the local pandemic dynamic and estimate how far from herd immunity Mongolia will be following-up with vaccination programme in 2021 and 2022. Funding: World Health Organisation, WHO UNITY Studies initiative, with funding by the COVID-19 Solidarity Response Fund and the German Federal Ministry of Health (BMG) COVID-19 Research and development. Translation: Cyrillic and Traditional Mongolian translation of abstract is available on appendix section.Battogtokh ChimeddorjUndram MandakhLinh-Vi LeBatzorig BayartsogtZolzaya DelegOyunsuren EnebishOyunbaatar AltanbayarBattur MagvanAnuujin GantumurOtgonjargal ByambaaGerelmaa EnebishBat-Erdene SaindooMandakhnaran DavaadorjAvarzed AmgalanbaatarKhangai EnkhtugsUsukhbayar MunkhbayarBatkhuu BayanjargalTuyajargal BadamsambuuMyagmartseren DashtserenZolmunkh NarmandakhKhongorzul TogooEnkh-Amar BoldbaatarAriunzaya Bat-ErdeneYerkyebulan MukhtarOyu-Erdene ShagdarsurenMandukhai GanbatOchbadrakh BatjargalBayasgalantai BavuusurenBatzaya BatchuluunGereltsetseg ZulmunkhGanbaatar ByambatsogtKhurelbaatar NyamdavaaTserendagva DalkhDamdindorj BoldbaatarTuvshinjargal TserenDarambazar GantulgaOtgonbayar DamdinbazarByambasuren VanchinLorenzo SubissiIsabel BergeriDavaalkham DambadarjaaNymadawa PagbajabynGregory GreifRyenchindorj ErkhembayarElsevierarticleSARS-CoV-2COVID-19PandemicsSeroepidemiological studiesMongoliaSeroprevalencePublic aspects of medicineRA1-1270ENThe Lancet Regional Health. Western Pacific, Vol 17, Iss , Pp 100317- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	SARS-CoV-2 COVID-19 Pandemics Seroepidemiological studies Mongolia Seroprevalence Public aspects of medicine RA1-1270
spellingShingle	SARS-CoV-2 COVID-19 Pandemics Seroepidemiological studies Mongolia Seroprevalence Public aspects of medicine RA1-1270 Battogtokh Chimeddorj Undram Mandakh Linh-Vi Le Batzorig Bayartsogt Zolzaya Deleg Oyunsuren Enebish Oyunbaatar Altanbayar Battur Magvan Anuujin Gantumur Otgonjargal Byambaa Gerelmaa Enebish Bat-Erdene Saindoo Mandakhnaran Davaadorj Avarzed Amgalanbaatar Khangai Enkhtugs Usukhbayar Munkhbayar Batkhuu Bayanjargal Tuyajargal Badamsambuu Myagmartseren Dashtseren Zolmunkh Narmandakh Khongorzul Togoo Enkh-Amar Boldbaatar Ariunzaya Bat-Erdene Yerkyebulan Mukhtar Oyu-Erdene Shagdarsuren Mandukhai Ganbat Ochbadrakh Batjargal Bayasgalantai Bavuusuren Batzaya Batchuluun Gereltsetseg Zulmunkh Ganbaatar Byambatsogt Khurelbaatar Nyamdavaa Tserendagva Dalkh Damdindorj Boldbaatar Tuvshinjargal Tseren Darambazar Gantulga Otgonbayar Damdinbazar Byambasuren Vanchin Lorenzo Subissi Isabel Bergeri Davaalkham Dambadarjaa Nymadawa Pagbajabyn Gregory Greif Ryenchindorj Erkhembayar SARS-CoV-2 seroprevalence in Mongolia: Results from a national population survey
description	Summary: Background: With the global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in early 2020, Mongolia implemented rapid emergency measures and did not report local transmission until November 2020. We conducted a national seroprevalence survey to monitor the burden of SARS-CoV-2 in Mongolia in the months surrounding the first local transmission. Methods: During October-December 2020, participants were randomly selected using age stratification and invited for interviews and blood samples at local primary health centres. We screened for total SARS-CoV-2 antibodies, followed by two-step quantitative SARS-CoV-2 IgG serology tests for positive samples. Weighted and test-adjusted seroprevalences were estimated. We used chi-square, Fisher's exact and other tests to identify variables associated with seropositivity. Findings: A total of 5000 subjects were enrolled. We detected SARS-CoV-2 IgG antibodies in 72 samples. Crude seroprevalence of SARS-CoV-2 antibodies was 1·44% (95%CI,1·21-1·67). Population weighted and test-adjusted seroprevalences were 1·36% (95%CI,1·11-1·63) and 1·45% (95%CI,1·11-1·63), respectively. Age, sex, geographical, and occupational factors were not associated with seropositivity (p>0·05). Symptoms and signs within past 3 months and seropositivity were not associated at the time of the survey (p>0·05). Interpretation: SARS-CoV-2 seroprevalence in Mongolia was low in the first year of the pandemic potentially due to strong public health measures, including border restrictions, educational facilities closure, earlier adoption of mask-wearing and others. Our findings suggest large-scale community transmission could not have occurred up to November 2020 in Mongolia. Additional serosurveys are needed to monitor the local pandemic dynamic and estimate how far from herd immunity Mongolia will be following-up with vaccination programme in 2021 and 2022. Funding: World Health Organisation, WHO UNITY Studies initiative, with funding by the COVID-19 Solidarity Response Fund and the German Federal Ministry of Health (BMG) COVID-19 Research and development. Translation: Cyrillic and Traditional Mongolian translation of abstract is available on appendix section.
format	article
author	Battogtokh Chimeddorj Undram Mandakh Linh-Vi Le Batzorig Bayartsogt Zolzaya Deleg Oyunsuren Enebish Oyunbaatar Altanbayar Battur Magvan Anuujin Gantumur Otgonjargal Byambaa Gerelmaa Enebish Bat-Erdene Saindoo Mandakhnaran Davaadorj Avarzed Amgalanbaatar Khangai Enkhtugs Usukhbayar Munkhbayar Batkhuu Bayanjargal Tuyajargal Badamsambuu Myagmartseren Dashtseren Zolmunkh Narmandakh Khongorzul Togoo Enkh-Amar Boldbaatar Ariunzaya Bat-Erdene Yerkyebulan Mukhtar Oyu-Erdene Shagdarsuren Mandukhai Ganbat Ochbadrakh Batjargal Bayasgalantai Bavuusuren Batzaya Batchuluun Gereltsetseg Zulmunkh Ganbaatar Byambatsogt Khurelbaatar Nyamdavaa Tserendagva Dalkh Damdindorj Boldbaatar Tuvshinjargal Tseren Darambazar Gantulga Otgonbayar Damdinbazar Byambasuren Vanchin Lorenzo Subissi Isabel Bergeri Davaalkham Dambadarjaa Nymadawa Pagbajabyn Gregory Greif Ryenchindorj Erkhembayar
author_facet	Battogtokh Chimeddorj Undram Mandakh Linh-Vi Le Batzorig Bayartsogt Zolzaya Deleg Oyunsuren Enebish Oyunbaatar Altanbayar Battur Magvan Anuujin Gantumur Otgonjargal Byambaa Gerelmaa Enebish Bat-Erdene Saindoo Mandakhnaran Davaadorj Avarzed Amgalanbaatar Khangai Enkhtugs Usukhbayar Munkhbayar Batkhuu Bayanjargal Tuyajargal Badamsambuu Myagmartseren Dashtseren Zolmunkh Narmandakh Khongorzul Togoo Enkh-Amar Boldbaatar Ariunzaya Bat-Erdene Yerkyebulan Mukhtar Oyu-Erdene Shagdarsuren Mandukhai Ganbat Ochbadrakh Batjargal Bayasgalantai Bavuusuren Batzaya Batchuluun Gereltsetseg Zulmunkh Ganbaatar Byambatsogt Khurelbaatar Nyamdavaa Tserendagva Dalkh Damdindorj Boldbaatar Tuvshinjargal Tseren Darambazar Gantulga Otgonbayar Damdinbazar Byambasuren Vanchin Lorenzo Subissi Isabel Bergeri Davaalkham Dambadarjaa Nymadawa Pagbajabyn Gregory Greif Ryenchindorj Erkhembayar
author_sort	Battogtokh Chimeddorj
title	SARS-CoV-2 seroprevalence in Mongolia: Results from a national population survey
title_short	SARS-CoV-2 seroprevalence in Mongolia: Results from a national population survey
title_full	SARS-CoV-2 seroprevalence in Mongolia: Results from a national population survey
title_fullStr	SARS-CoV-2 seroprevalence in Mongolia: Results from a national population survey
title_full_unstemmed	SARS-CoV-2 seroprevalence in Mongolia: Results from a national population survey
title_sort	sars-cov-2 seroprevalence in mongolia: results from a national population survey
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/908f608d11284685ab8ab11de81d0e0b
work_keys_str_mv	AT battogtokhchimeddorj sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT undrammandakh sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT linhvile sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT batzorigbayartsogt sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT zolzayadeleg sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT oyunsurenenebish sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT oyunbaataraltanbayar sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT batturmagvan sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT anuujingantumur sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT otgonjargalbyambaa sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT gerelmaaenebish sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT baterdenesaindoo sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT mandakhnarandavaadorj sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT avarzedamgalanbaatar sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT khangaienkhtugs sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT usukhbayarmunkhbayar sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT batkhuubayanjargal sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT tuyajargalbadamsambuu sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT myagmartserendashtseren sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT zolmunkhnarmandakh sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT khongorzultogoo sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT enkhamarboldbaatar sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT ariunzayabaterdene sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT yerkyebulanmukhtar sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT oyuerdeneshagdarsuren sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT mandukhaiganbat sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT ochbadrakhbatjargal sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT bayasgalantaibavuusuren sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT batzayabatchuluun sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT gereltsetsegzulmunkh sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT ganbaatarbyambatsogt sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT khurelbaatarnyamdavaa sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT tserendagvadalkh sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT damdindorjboldbaatar sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT tuvshinjargaltseren sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT darambazargantulga sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT otgonbayardamdinbazar sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT byambasurenvanchin sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT lorenzosubissi sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT isabelbergeri sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT davaalkhamdambadarjaa sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT nymadawapagbajabyn sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT gregorygreif sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey AT ryenchindorjerkhembayar sarscov2seroprevalenceinmongoliaresultsfromanationalpopulationsurvey
_version_	1718415925530591232

SARS-CoV-2 seroprevalence in Mongolia: Results from a national population survey

Ejemplares similares