Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop
Ebola virus remains a global threat to public health and biosecurity, yet we still know relatively little about its pathogenesis and the complications that arise following recovery. With nearly 20,000 survivors from the 2013–2016 West African outbreak, as well as over 1,000 survivors of the recent...
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American Society for Microbiology
2021
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oai:doaj.org-article:909040b19d774466a013d0a904fb9c042021-11-03T18:15:38ZAtypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop2161-21292150-751110.1128/mBio.01438-20https://doaj.org/article/909040b19d774466a013d0a904fb9c042021-02-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01438-20https://doaj.org/toc/2161-2129https://doaj.org/toc/2150-7511 Ebola virus remains a global threat to public health and biosecurity, yet we still know relatively little about its pathogenesis and the complications that arise following recovery. With nearly 20,000 survivors from the 2013–2016 West African outbreak, as well as over 1,000 survivors of the recent outbreak in the DRC, we must consider the consequences of virus persistence and recrudescent disease, even if they are rare.Logan BanadygaWenjun ZhuShweta KailasanKatie A. HowellKrzysztof FranaszekShihua HeVinayakumar SiragamKeding ChengFeihu YanEstella MoffatWenguang CaoAnders LeungCarissa Embury-HyattM. Javad AmanXiangguo QiuAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 1 (2021) |
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DOAJ |
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| topic |
Microbiology QR1-502 |
| spellingShingle |
Microbiology QR1-502 Logan Banadyga Wenjun Zhu Shweta Kailasan Katie A. Howell Krzysztof Franaszek Shihua He Vinayakumar Siragam Keding Cheng Feihu Yan Estella Moffat Wenguang Cao Anders Leung Carissa Embury-Hyatt M. Javad Aman Xiangguo Qiu Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop |
| description |
Ebola virus remains a global threat to public health and biosecurity, yet we still know relatively little about its pathogenesis and the complications that arise following recovery. With nearly 20,000 survivors from the 2013–2016 West African outbreak, as well as over 1,000 survivors of the recent outbreak in the DRC, we must consider the consequences of virus persistence and recrudescent disease, even if they are rare. |
| format |
article |
| author |
Logan Banadyga Wenjun Zhu Shweta Kailasan Katie A. Howell Krzysztof Franaszek Shihua He Vinayakumar Siragam Keding Cheng Feihu Yan Estella Moffat Wenguang Cao Anders Leung Carissa Embury-Hyatt M. Javad Aman Xiangguo Qiu |
| author_facet |
Logan Banadyga Wenjun Zhu Shweta Kailasan Katie A. Howell Krzysztof Franaszek Shihua He Vinayakumar Siragam Keding Cheng Feihu Yan Estella Moffat Wenguang Cao Anders Leung Carissa Embury-Hyatt M. Javad Aman Xiangguo Qiu |
| author_sort |
Logan Banadyga |
| title |
Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop |
| title_short |
Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop |
| title_full |
Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop |
| title_fullStr |
Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop |
| title_full_unstemmed |
Atypical Ebola Virus Disease in a Nonhuman Primate following Monoclonal Antibody Treatment Is Associated with Glycoprotein Mutations within the Fusion Loop |
| title_sort |
atypical ebola virus disease in a nonhuman primate following monoclonal antibody treatment is associated with glycoprotein mutations within the fusion loop |
| publisher |
American Society for Microbiology |
| publishDate |
2021 |
| url |
https://doaj.org/article/909040b19d774466a013d0a904fb9c04 |
| work_keys_str_mv |
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