CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors
Adipose tissue contains macrophages that can influence both local and systemic metabolism via the secretion of cytokines. Here, Nawaz et al. report that M2-like macrophages, present in adipose tissue, create a microenvironment that inhibits proliferation of adipocyte progenitors due to the secretion...
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Nature Portfolio
2017
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oai:doaj.org-article:9090702baf8947208fa65b827ea3ad272021-12-02T13:57:54ZCD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors10.1038/s41467-017-00231-12041-1723https://doaj.org/article/9090702baf8947208fa65b827ea3ad272017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00231-1https://doaj.org/toc/2041-1723Adipose tissue contains macrophages that can influence both local and systemic metabolism via the secretion of cytokines. Here, Nawaz et al. report that M2-like macrophages, present in adipose tissue, create a microenvironment that inhibits proliferation of adipocyte progenitors due to the secretion of TGF-β1Allah NawazAminuddin AminuddinTomonobu KadoAkiko TakikawaSeiji YamamotoKoichi TsuneyamaYoshiko IgarashiMasashi IkutaniYasuhiro NishidaYoshinori NagaiKiyoshi TakatsuJohji ImuraMasakiyo SasaharaYukiko OkazakiKohjiro UekiTadashi OkamuraKumpei TokuyamaAkira AndoMichihiro MatsumotoHisashi MoriTakashi NakagawaNorihiko KobayashiKumiko SaekiIsao UsuiShiho FujisakaKazuyuki TobeNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017) |
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Science Q Allah Nawaz Aminuddin Aminuddin Tomonobu Kado Akiko Takikawa Seiji Yamamoto Koichi Tsuneyama Yoshiko Igarashi Masashi Ikutani Yasuhiro Nishida Yoshinori Nagai Kiyoshi Takatsu Johji Imura Masakiyo Sasahara Yukiko Okazaki Kohjiro Ueki Tadashi Okamura Kumpei Tokuyama Akira Ando Michihiro Matsumoto Hisashi Mori Takashi Nakagawa Norihiko Kobayashi Kumiko Saeki Isao Usui Shiho Fujisaka Kazuyuki Tobe CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors |
| description |
Adipose tissue contains macrophages that can influence both local and systemic metabolism via the secretion of cytokines. Here, Nawaz et al. report that M2-like macrophages, present in adipose tissue, create a microenvironment that inhibits proliferation of adipocyte progenitors due to the secretion of TGF-β1 |
| format |
article |
| author |
Allah Nawaz Aminuddin Aminuddin Tomonobu Kado Akiko Takikawa Seiji Yamamoto Koichi Tsuneyama Yoshiko Igarashi Masashi Ikutani Yasuhiro Nishida Yoshinori Nagai Kiyoshi Takatsu Johji Imura Masakiyo Sasahara Yukiko Okazaki Kohjiro Ueki Tadashi Okamura Kumpei Tokuyama Akira Ando Michihiro Matsumoto Hisashi Mori Takashi Nakagawa Norihiko Kobayashi Kumiko Saeki Isao Usui Shiho Fujisaka Kazuyuki Tobe |
| author_facet |
Allah Nawaz Aminuddin Aminuddin Tomonobu Kado Akiko Takikawa Seiji Yamamoto Koichi Tsuneyama Yoshiko Igarashi Masashi Ikutani Yasuhiro Nishida Yoshinori Nagai Kiyoshi Takatsu Johji Imura Masakiyo Sasahara Yukiko Okazaki Kohjiro Ueki Tadashi Okamura Kumpei Tokuyama Akira Ando Michihiro Matsumoto Hisashi Mori Takashi Nakagawa Norihiko Kobayashi Kumiko Saeki Isao Usui Shiho Fujisaka Kazuyuki Tobe |
| author_sort |
Allah Nawaz |
| title |
CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors |
| title_short |
CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors |
| title_full |
CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors |
| title_fullStr |
CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors |
| title_full_unstemmed |
CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors |
| title_sort |
cd206+ m2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/9090702baf8947208fa65b827ea3ad27 |
| work_keys_str_mv |
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| _version_ |
1718392273190780928 |