Impact of Plasma Donepezil Concentration on Behavioral and Psychological Symptoms of Dementia in Patients with Alzheimer’s Disease

Impact of Plasma Donepezil Concentration on Behavioral and Psychological Symptoms of Dementia in Patients with Alzheimer’s Disease

Background/Aims: The behavioral and psychological symptoms of dementia (BPSD) detract from the quality of life of not only dementia patients but also their family members and caregivers. Donepezil is used to treat Alzheimer’s disease and is metabolized via cytochrome P450 (CYP) 2D6 and CYP3A4/5. It...

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Autores principales: Yoshiyuki Kagawa, Yoshiaki Yamamoto, Ayami Ueno, Kengo Inomata, Mayu Tezuka, Takashi Osawa, Yasuharu Yazawa, Toshio Maeda, Tomokazu Obi
Formato: article
Lenguaje:EN
Publicado: Karger Publishers 2021
Materias:
alzheimer’s disease
behavioral and psychological symptoms of dementia
donepezil
pharmacokinetics
polymorphism
Neurology. Diseases of the nervous system
RC346-429
Geriatrics
RC952-954.6
Acceso en línea:https://doaj.org/article/9092d961ecd94bbf8758a46b3d1fdcea
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