Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss

Activation of the NRF2 pathway in Keap1-knockdown mice attenuates progression of age-related hearing loss

Abstract Age-related hearing loss (AHL) is a progressive sensorineural hearing loss in elderly people. Although no prevention or treatments have been established for AHL, recent studies have demonstrated that oxidative stress is closely related to pathogenesis of AHL, suggesting that suppression of...

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Autores principales: Tetsuya Oishi, Daisuke Matsumaru, Nao Ota, Hiroshi Kitamura, Tianxiang Zhang, Yohei Honkura, Yukio Katori, Hozumi Motohashi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Geriatrics
RC952-954.6
Acceso en línea:https://doaj.org/article/90942eff5eaa478aa91b20376ff615a1
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