Chromatin accessibility of circulating CD8+ T cells predicts treatment response to PD-1 blockade in patients with gastric cancer

Chromatin accessibility of circulating CD8+ T cells predicts treatment response to PD-1 blockade in patients with gastric cancer

Anti-PD-1 therapy could induce a durable response in patients with gastric cancer, however biomarkers to predict response to immunotherapy are generally lacking. Here the authors report that openness of chromatin in circulating CD8+ T cells predicts treatment outcome in patients with metastatic gast...

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Autores principales: Hyun Mu Shin, Gwanghun Kim, Sangjib Kim, Ji Hyun Sim, Jiyeob Choi, Minji Kim, Minsuk Kwon, Sang-Kyu Ye, Dong-Sup Lee, Seung Woo Cho, Seung Tae Kim, Jeeyun Lee, Hang-Rae Kim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/90aa9faac7854b7a8f1dcadb3ad37005
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