Chromatin accessibility of circulating CD8+ T cells predicts treatment response to PD-1 blockade in patients with gastric cancer
Anti-PD-1 therapy could induce a durable response in patients with gastric cancer, however biomarkers to predict response to immunotherapy are generally lacking. Here the authors report that openness of chromatin in circulating CD8+ T cells predicts treatment outcome in patients with metastatic gast...
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Auteurs principaux: | Hyun Mu Shin, Gwanghun Kim, Sangjib Kim, Ji Hyun Sim, Jiyeob Choi, Minji Kim, Minsuk Kwon, Sang-Kyu Ye, Dong-Sup Lee, Seung Woo Cho, Seung Tae Kim, Jeeyun Lee, Hang-Rae Kim |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/90aa9faac7854b7a8f1dcadb3ad37005 |
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