A novel artificial intelligence-based approach for identification of deoxynucleotide aptamers.

The selection of a DNA aptamer through the Systematic Evolution of Ligands by EXponential enrichment (SELEX) method involves multiple binding steps, in which a target and a library of randomized DNA sequences are mixed for selection of a single, nucleotide-specific molecule. Usually, 10 to 20 steps...

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Autores principales: Frances L Heredia, Abiel Roche-Lima, Elsie I Parés-Matos
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/90b10effa3d343cc8031849e24ff62c6
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