In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case
Complete response can be difficult to assess after isolated limb perfusion (ILP) for metastatic in-transit melanoma, especially when numerous and unresectable post-necrotic persisting pigmented lesions occur. These residual lesions are mainly seen in the more superficial and pigmented types of meta...
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Mattioli1885
2017
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oai:doaj.org-article:90bb85c23af84a5d867828018de0122d2021-11-17T08:30:49ZIn vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case10.5826/dpc.0702a102160-9381https://doaj.org/article/90bb85c23af84a5d867828018de0122d2017-05-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/208https://doaj.org/toc/2160-9381 Complete response can be difficult to assess after isolated limb perfusion (ILP) for metastatic in-transit melanoma, especially when numerous and unresectable post-necrotic persisting pigmented lesions occur. These residual lesions are mainly seen in the more superficial and pigmented types of metastatic disease and correspond to the residual melanophage granuloma that persists after tumor tissues undergo complete necrosis. Reflectance confocal microscopy (RCM) is a non-invasive technique that allows the exploration of the superficial dermis. Here, we present the case of a patient in whom numerous post-ILP limb residual pigmented lesions were explored using combined RCM and histological examination of sample lesions and could be characterized as non-active. This approach allowed us to avoid additional excisions. Rastine MeratWolf-Henning BoehnckeGürkan KayaMattioli1885articlereflectance confocal microscopyisolated limb perfusionmetastatic melanomaDermatologyRL1-803ENDermatology Practical & Conceptual, Vol 7, Iss 2 (2017) |
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reflectance confocal microscopy isolated limb perfusion metastatic melanoma Dermatology RL1-803 |
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reflectance confocal microscopy isolated limb perfusion metastatic melanoma Dermatology RL1-803 Rastine Merat Wolf-Henning Boehncke Gürkan Kaya In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case |
| description |
Complete response can be difficult to assess after isolated limb perfusion (ILP) for metastatic in-transit melanoma, especially when numerous and unresectable post-necrotic persisting pigmented lesions occur. These residual lesions are mainly seen in the more superficial and pigmented types of metastatic disease and correspond to the residual melanophage granuloma that persists after tumor tissues undergo complete necrosis. Reflectance confocal microscopy (RCM) is a non-invasive technique that allows the exploration of the superficial dermis. Here, we present the case of a patient in whom numerous post-ILP limb residual pigmented lesions were explored using combined RCM and histological examination of sample lesions and could be characterized as non-active. This approach allowed us to avoid additional excisions.
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| format |
article |
| author |
Rastine Merat Wolf-Henning Boehncke Gürkan Kaya |
| author_facet |
Rastine Merat Wolf-Henning Boehncke Gürkan Kaya |
| author_sort |
Rastine Merat |
| title |
In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case |
| title_short |
In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case |
| title_full |
In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case |
| title_fullStr |
In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case |
| title_full_unstemmed |
In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case |
| title_sort |
in vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. report of a case |
| publisher |
Mattioli1885 |
| publishDate |
2017 |
| url |
https://doaj.org/article/90bb85c23af84a5d867828018de0122d |
| work_keys_str_mv |
AT rastinemerat invivoreflectanceconfocalmicroscopyausefulnoninvasivetooltoassesstheresponsetoisolatedlimbperfusionforsuperficialpigmentedmelanomaintransitmetastaticdiseasereportofacase AT wolfhenningboehncke invivoreflectanceconfocalmicroscopyausefulnoninvasivetooltoassesstheresponsetoisolatedlimbperfusionforsuperficialpigmentedmelanomaintransitmetastaticdiseasereportofacase AT gurkankaya invivoreflectanceconfocalmicroscopyausefulnoninvasivetooltoassesstheresponsetoisolatedlimbperfusionforsuperficialpigmentedmelanomaintransitmetastaticdiseasereportofacase |
| _version_ |
1718425750922592256 |