Genetically encoded protein photocrosslinker with a transferable mass spectrometry-identifiable label

Genetically encoded protein photocrosslinker with a transferable mass spectrometry-identifiable label

Mapping protein-protein interaction using crosslinking and mass spectroscopy strategies is hampered by a high rate of false-positive results. Here, the authors develop a genetically encoded photo-affinity probe for accurate identification of protein interaction partners and crosslinking sites.

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Detalles Bibliográficos
Autores principales: Yi Yang, Haiping Song, Dan He, Shuai Zhang, Shizhong Dai, Shixian Lin, Rong Meng, Chu Wang, Peng R. Chen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
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Acceso en línea:https://doaj.org/article/90bd7af9d1c84c018858e3904496dd5c
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