Genetically encoded protein photocrosslinker with a transferable mass spectrometry-identifiable label
Mapping protein-protein interaction using crosslinking and mass spectroscopy strategies is hampered by a high rate of false-positive results. Here, the authors develop a genetically encoded photo-affinity probe for accurate identification of protein interaction partners and crosslinking sites.
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Main Authors: | Yi Yang, Haiping Song, Dan He, Shuai Zhang, Shizhong Dai, Shixian Lin, Rong Meng, Chu Wang, Peng R. Chen |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Online Access: | https://doaj.org/article/90bd7af9d1c84c018858e3904496dd5c |
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