Pre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV

Boosting of maternal antibodies against RSV is a potential approach to protect infants from severe infection, but data from animal models is missing. Here Steff et al. test two different boosts in seropositive cattle pre-exposed to bovine RSV and show that pre-fusion F strongly boosts neutralizing r...

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Autores principales: Ann-Muriel Steff, James Monroe, Kristian Friedrich, Sumana Chandramouli, Thi Lien-Anh Nguyen, Sai Tian, Sarah Vandepaer, Jean-François Toussaint, Andrea Carfi
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/90d01f4f5f024e2b9891e46dfce295b2
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spelling oai:doaj.org-article:90d01f4f5f024e2b9891e46dfce295b22021-12-02T15:38:49ZPre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV10.1038/s41467-017-01092-42041-1723https://doaj.org/article/90d01f4f5f024e2b9891e46dfce295b22017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01092-4https://doaj.org/toc/2041-1723Boosting of maternal antibodies against RSV is a potential approach to protect infants from severe infection, but data from animal models is missing. Here Steff et al. test two different boosts in seropositive cattle pre-exposed to bovine RSV and show that pre-fusion F strongly boosts neutralizing responses.Ann-Muriel SteffJames MonroeKristian FriedrichSumana ChandramouliThi Lien-Anh NguyenSai TianSarah VandepaerJean-François ToussaintAndrea CarfiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ann-Muriel Steff
James Monroe
Kristian Friedrich
Sumana Chandramouli
Thi Lien-Anh Nguyen
Sai Tian
Sarah Vandepaer
Jean-François Toussaint
Andrea Carfi
Pre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV
description Boosting of maternal antibodies against RSV is a potential approach to protect infants from severe infection, but data from animal models is missing. Here Steff et al. test two different boosts in seropositive cattle pre-exposed to bovine RSV and show that pre-fusion F strongly boosts neutralizing responses.
format article
author Ann-Muriel Steff
James Monroe
Kristian Friedrich
Sumana Chandramouli
Thi Lien-Anh Nguyen
Sai Tian
Sarah Vandepaer
Jean-François Toussaint
Andrea Carfi
author_facet Ann-Muriel Steff
James Monroe
Kristian Friedrich
Sumana Chandramouli
Thi Lien-Anh Nguyen
Sai Tian
Sarah Vandepaer
Jean-François Toussaint
Andrea Carfi
author_sort Ann-Muriel Steff
title Pre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV
title_short Pre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV
title_full Pre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV
title_fullStr Pre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV
title_full_unstemmed Pre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV
title_sort pre-fusion rsv f strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine rsv
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/90d01f4f5f024e2b9891e46dfce295b2
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