Dermoscopic and confocal features of an axillary “special site” nevus

“Nevi of special sites” is a term that denotes melanocytic nevi presenting in specific anatomic locations including the scalp, genital area, flexural sites, and acral sites [1]. Nevi from these anatomic sites display at times histopathologic features that may lead the reading pathologist to recomme...

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Autores principales:	Riana Dutt, Harold S. Rabinovitz, Rajendra Singh, Alon Scope
Formato:	article
Lenguaje:	EN
Publicado:	Mattioli1885 2017
Materias:	Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/90d5416f59174479843087db9338ec9d
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spelling	oai:doaj.org-article:90d5416f59174479843087db9338ec9d2021-11-17T08:30:51ZDermoscopic and confocal features of an axillary “special site” nevus10.5826/dpc.0701a112160-9381https://doaj.org/article/90d5416f59174479843087db9338ec9d2017-02-01T00:00:00Zhttp://dpcj.org/index.php/dpc/article/view/235https://doaj.org/toc/2160-9381 “Nevi of special sites” is a term that denotes melanocytic nevi presenting in specific anatomic locations including the scalp, genital area, flexural sites, and acral sites [1]. Nevi from these anatomic sites display at times histopathologic features that may lead the reading pathologist to recommend re-excision of these benign nevi. Reflectance confocal microscopy (RCM) is a noninvasive imaging tool that allows for visualization of epidermal, dermal-epidermal junctional (DEJ), and superficial dermal tissue structures at cellular level resolution. RCM features of special site nevi have not been previously described in the literature. Defining the RCM characteristics of special site nevi may increase diagnostic accuracy and assist in ruling out melanoma. Here, we report a case of a pigmented lesion appearing in the axilla of a patient with a recently diagnosed melanoma. Dermoscopic and histopathologic results were consistent with the diagnosis of nevus in flexural anatomic sites. In this case, RCM showed a regular honeycomb pattern of epidermal keratinocytes and enlarged, non-homogenous, discohesive nests at the DEJ, a pattern that corresponded well with the histopathologic findings. Larger studies are needed to establish RCM features of special site nevi in order to reliably rule out melanoma and lower the rate of unnecessary excisions of these benign nevi. Riana DuttHarold S. RabinovitzRajendra SinghAlon ScopeMattioli1885articleDermatologyRL1-803ENDermatology Practical & Conceptual (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Dermatology RL1-803
spellingShingle	Dermatology RL1-803 Riana Dutt Harold S. Rabinovitz Rajendra Singh Alon Scope Dermoscopic and confocal features of an axillary “special site” nevus
description	“Nevi of special sites” is a term that denotes melanocytic nevi presenting in specific anatomic locations including the scalp, genital area, flexural sites, and acral sites [1]. Nevi from these anatomic sites display at times histopathologic features that may lead the reading pathologist to recommend re-excision of these benign nevi. Reflectance confocal microscopy (RCM) is a noninvasive imaging tool that allows for visualization of epidermal, dermal-epidermal junctional (DEJ), and superficial dermal tissue structures at cellular level resolution. RCM features of special site nevi have not been previously described in the literature. Defining the RCM characteristics of special site nevi may increase diagnostic accuracy and assist in ruling out melanoma. Here, we report a case of a pigmented lesion appearing in the axilla of a patient with a recently diagnosed melanoma. Dermoscopic and histopathologic results were consistent with the diagnosis of nevus in flexural anatomic sites. In this case, RCM showed a regular honeycomb pattern of epidermal keratinocytes and enlarged, non-homogenous, discohesive nests at the DEJ, a pattern that corresponded well with the histopathologic findings. Larger studies are needed to establish RCM features of special site nevi in order to reliably rule out melanoma and lower the rate of unnecessary excisions of these benign nevi.
format	article
author	Riana Dutt Harold S. Rabinovitz Rajendra Singh Alon Scope
author_facet	Riana Dutt Harold S. Rabinovitz Rajendra Singh Alon Scope
author_sort	Riana Dutt
title	Dermoscopic and confocal features of an axillary “special site” nevus
title_short	Dermoscopic and confocal features of an axillary “special site” nevus
title_full	Dermoscopic and confocal features of an axillary “special site” nevus
title_fullStr	Dermoscopic and confocal features of an axillary “special site” nevus
title_full_unstemmed	Dermoscopic and confocal features of an axillary “special site” nevus
title_sort	dermoscopic and confocal features of an axillary “special site” nevus
publisher	Mattioli1885
publishDate	2017
url	https://doaj.org/article/90d5416f59174479843087db9338ec9d
work_keys_str_mv	AT rianadutt dermoscopicandconfocalfeaturesofanaxillaryspecialsitenevus AT haroldsrabinovitz dermoscopicandconfocalfeaturesofanaxillaryspecialsitenevus AT rajendrasingh dermoscopicandconfocalfeaturesofanaxillaryspecialsitenevus AT alonscope dermoscopicandconfocalfeaturesofanaxillaryspecialsitenevus
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Dermoscopic and confocal features of an axillary “special site” nevus

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